The mechanism of fibrosis caused by free silica particles involves a lot of cells and reactions including inflammatory reaction,immunological reaction,foreign body reaction and cell toxic action.

• 游离二氧化硅致肺组织纤维化机制十分复杂,涉及多种细胞及生物活性物质参与的炎症反应、免疫反应、异物反应、细胞毒作用等。