The median age was 48 years(range, 33 to 56 years) KPS>70. CPT-11 was given at 60-80 mg/m~ 2 by intravenous infusion on days 1,8,15, and PDD given as 60-80 mg/m~ 2 by intravenous infusion.

• 接受顺铂60~80mg/m2联合开普拓60mg/m2第1、8、15天静脉滴注,每4周重复。