The number of Clara cells and the secretion of CC16 reduce in a rat model of COPD, which may be a mechanism for COPD.

• COPD大鼠的气道炎症可导致Clara细胞超微结构改变,Clara细胞数量及CC16的合成及分泌量减少,这可能与COPD的发生发展有一定的关系。