The positive granules for PDGF A and B chain mRNA expression were few in PASMC cultured in serum free medium(control group), but rich in PASMC exposed to PDGF BB polypeptide.

• 结果表明，无血清培养的肺动脉平滑肌细胞内PDGF?A和PDGF?B链mRNA阳性表达颗粒稀少，PDGF?BB多肽培养的肺动脉平滑肌细胞PDGF?A和PDGF?B链mRNA阳性表达颗粒增多，较密集的分布于整个细胞内。