The purpose of the present study in the discuss the pathnogenesis of diabetes neuropathy in DN mice model caused by STZ injection, and the pharmacological mechanism of Shen Xian Tang decoction.

• 本文的目的是在STZ糖尿病脑病变小鼠模型的基础上，探讨糖尿病性脑病变的发病机理，并观察中药参仙汤的药效及其作用机理。