The purpose of this study was to construct a cell line model that bcr/abl expression can be regulated by Tet-off inducing-expression-system.

• 本研究为构建能由Tet-off诱导表达系统调控bcr/abl融合基因表达的细胞系,为深入研究bcr/abl融合基因功能及其调控机制提供一种有价值的细胞模型。