The result shows that the modified lead compounds can decrease the toxicity and side effect efficiently, and enhance the pharmacal effect.
英
美
- 从单糖、二糖和寡糖、多糖三个层面,分别对糖及其衍生物与先导化合物的键合方式、经过结构修饰的先导化合物的生物活性变化作了综述。