The risk of HCC in creased significantly and showed an additive effect in patients with HBV and HCVcoinfection (OR= 42. 85).

• 但当HCV和HBV同时存在时；OR值为42.；85；明显高于HBV或HCV单独致肝癌的危险性；呈明显的协同作用或相加作用。