The stimulating effect of breast cancer cells on endothelial cell-proliferation is reduced by AR inhibition in vitro and in vivo, accompanied with expression supression of these active factors.

• 抑制AR表达后，乳腺癌细胞体外及体内刺激血管内皮细胞增值的能力被抑制，同时伴随着这些生物活性因子表达的降低。