The study, published in The FASEB Journal, shows that mice lacking IRS-1 had an average lifespan increase of 20 per cent when compared to normal mice.

• 小组研究了通过基因改造后缺少IRS-1或-2的老鼠。IRS通过胰岛素激活，胰岛素负责调节葡萄糖和脂肪代谢。