The underlying pathogenetic mechanism in XGP is renal outflow obstruction (often caused by Staghorn calculi) in the setting of suppuratie inflammation.

• 黄色肉芽肿性肾盂肾炎（XGP）病人的发病原因为长期肾内流出道梗阻（常见原因为鹿角样结石）所致的化脓性炎症。