Then determine the organ coefficient,and the contents of dopamine(DA),norepinephrine(NE),5-hydroxytryptamine(5-HT)and homovanillic acid(HVA)in brain with high performance liquid chromatography(HPLC).

• 连续1个月经口灌胃染毒后,测定脏器系数并采用高效液相色谱(HPLC)荧光检测法分别检测雄性小鼠全脑中多巴胺(DA)、去甲肾上腺素(NE)、5-羟色胺(5-HT)的含量。