This study was aimed to observe whether expressions of JAK2, STAT1, STAT5 proteins in indomethacin treated CML cells involved in the proliferation inhibition of CML cells, and elucidate the pharmacological mechanism of indomethacin anti leukemia.

• 本研究的目的是观察吲哚美辛作用下慢性粒细胞白血病 (CML)细胞增殖抑制过程中JAK2、STAT1和STAT5蛋白质表达水平的变化及细胞内分布 ,揭示吲哚美辛抑制CML细胞增殖的分子机制。