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- Thymidine Phespherylase 胸苷磷酸化酶
- Objective Preparition of monoclone antibody to human thymidine kinase(hTK). 目的制备人胸苷激酶单克隆抗体。
- Mechanism of Action: Stavudine, a nucleoside analogue of thymidine, inhibits the replication of HIV in human cells in vitro. 司他夫定是胸苷核苷类似物，可抑制HIV病毒在人体细胞内的复制。
- Aim: To explore the expression of thymidine phosphorylase (TP) in esophageal carcinoma tissue and its significance. 目的:探讨食管癌组织中胸苷磷酸化酶(TP)的表达情况及意义。
- The mechanism is related primarily to 2-deoxy-D-ribose(2-dDR), the product of thymidine by TP specially. 其作用机制主要与TP 特异作用于胸苷后的产物2 -脱氧- D -核糖(2-dDR)有关。
- Zhang JM, et al. Expression of thymidine phosphorylase by macrophages in colorectal cancer tissues. 张继民，等.;结直肠癌组织中巨噬细胞表达胸苷磷酸化酶并与血管新生相关
- DNA and protein synthesis was detected by [3H]thymidine as well as [3H]TdR incorporation,respectively. [3H]亮氨酸掺入法及[3H]胸腺嘧啶核苷掺入法检测细胞内蛋白、DNA合成。
- These three hormones also robustly stimulated thymidine incorporation and inhibited drug-induced apoptosis. 并且这三种激素有利于胸（腺嘧啶脱氧核）苷掺入和抑制药物诱导的细胞凋亡。
- The reaction mechanism of enzymatic synthesis of thymidine was reviewed, and 6 examples of application were given. 综述了酶法合成胸苷的反应机理，并列举了6个应用实例。
- Objective To evaluate the bystander effect in the retrovirus vector the herpes simplex virus thymidine kinase gene Ganciclovir system (RV HSV tk GCV). 目的 研究反转录病毒载体 (RV) -单纯疱疹病毒胸苷激酶基因 (HSV tK) -环丙氧苷 (GCV)系统中的旁观者效应。
- We have identified conserved domains of the thymidine kinase proteins of the alpha herpes viruses:-R*Y*DG**G*GK*T-and-FDRHP*A***C*P*AR-. 在氨基酸序列中发现有疱疹病毒TK基因的保守序列R*Y*DG**G*GK*T-和-FDRHP*A***C*P*AR-。
- We have studied several factors affecting the uptake of [~3H] thymidine ([~3H]TdR) by the fresh spleen nucleated cells isolated from C57BL mice. 本文以测定氚化胸腺嘧啶核苷(~3H-TdR)掺入新鲜制备的离体的小鼠脾有核细胞DNA的方法;来判断细胞DNA合成能力;并对影响脾细胞DNA合成的某些基本因素的作用进行了研究。 研究表明;2毫升pH7.;4的Eagle培养液中含4×10(?)
- Thymine and the objective product,2'-deoxyadenosine,were enzymatically transferred from thymidine and adenine by Brevibacterium acetylium. 胸苷和腺嘌呤在乙酰短杆菌作用下转化成胸腺嘧啶和目标产物2’-脱氧腺苷。
- The second nucleotide in optimal human CpG motifs was thymidine, while in less active human CpG motifs or optimal murine CpG motifs, it was purines. 5′ GTCGTT 3′和 5′ GTCGTC 3′ 2个基序对人B细胞有高度免疫刺激活性 ,第二位碱基均为“T” ,而在小鼠CpG基序中该位碱基为“G”或“A”。
- The expression of thymidine phosphorylase (TP/PD-ECGF) in the tumor tissue was determined by the immunohistochemical method . 采用免疫组化法检测肿瘤组织中的TP的染色强度和染色面积。
- ILTV has thymidine kinase ( TK ) gene which has been shown is associated with its virulence and reactivation from the latent state. TK ) 病毒毒力基因，此基因与病毒毒力及病毒于潜伏期再活化的能力有关。
- Objective To study the mechanism of bystander effect in herpes simplex virus thymidine kinase(HSV TK)/Ganciclovir(GCV) mediated gene therapy. 目的 探讨用单纯疱疹病毒胸腺嘧啶核苷激酶（HSV?TK）/丙氧鸟苷（GCV） 系统进行基因治疗时发生的旁观者效应机制。
- Next, patients are given an antiviral drug, Ganciclovir, which the thymidine kinase then converts into a substance that destroys all dividing cells. 接下来，将抗病毒药物Ganciclovir注射到病人体内，Ganciclovir能将胸苷激酶转化为一种能杀死所有分裂细胞的物质。
- Shen Q, Yang CM, Zhang GC, et al.Effects of excess thymidine on expression of cyclin[J].J Fouth Mil Med Univ, 2003, 24(6): 510-2. [5]沈青;杨存明;张国成;等.;过量胸苷对细胞周期素表达的影响[J]
- Objective: To observe the killing effect of Herpes Simplex Virus thymidine kinase gene/Acyclovir system(HSV tk/ACV) on human hepatocarcinoma cells in vitro. 目的 :观察单纯疱疹病毒胸苷激酶基因 (HSV - tk基因 ,自杀基因 )与阿昔洛韦 (ACV)系统对人肝癌细胞的体外杀伤效果。
