To explore the underlying pathophysiologic mechanisms of risk factor aggregation in causing CVD by using prospective cohort study is of utmost importance in guiding CVD community control.

• 采用前瞻队列研究方法探讨不同危险因素聚集的致心血管病作用及其病理生理机制和量效关系对指导人群防治有重要意义。