To improve the performance of assays on the oligonucleotide microarray, the factors that influence the hybridization effects such as surface chemistry, probe size, spacer length, hybridization conditions etc were intensely studied and optimized.

• 为改善寡核苷酸芯片的分析性能，对影响芯片杂交结果的因素，如片基表面的化学处理、探针的长度、间隔臂的长度、杂交条件等，进行了深入的研究和优化。