To this end National drug regulatory agencies approved three bezoar substitutes namely: artificial bezoar and foster the bezoar and the ICCB one by one since 1972.

• 为此，国家药品监督管理部门自1972年陆续批准了3个牛黄代用品，即：人工牛黄、培植牛黄和体外培育牛黄。