Treatment with Fc-OPG significantly reduced the calcified lesion area without affecting atherosclerotic lesion size or number, vascular cytokines, or plasma cholesterol levels.

• 用Fc-OPG处理的小鼠显著减小了钙化组织的面积而没有影响动脉粥样硬化损伤的面积大小和数量，以及血管因子、血浆胆固醇水平。