Two of them died and one left hospital for intolerance of the side effects of amphotericin B. [Conclusion] In the endemic period of AIDS, we should pay more attention to Penicilliosis marneffei.

• 确诊有赖于涂片镜检、真菌培养及组织病理发现马尔尼菲青霉菌。其中1例不能耐受两性霉素B付反应，自动出院；另2例死亡。