Ultimately, knockout mice deeloped cardiac hypertrophy and heart failure, which inoles protein kinase C signal transduction but not the mitogen-actiated protein kinase pathway.

• 最终结果是基因敲除小鼠心脏发生肥厚和心衰，与蛋白激酶C信号转导有关而与丝裂原激活蛋白激酶途径无关。