VBE is caused by leaking out of protein and water from capillaries through damaged blood-brain barrier(BBB),it is protein- rich edema and white matter condition is serious than gray matter.

• VBE的病理基础是血脑屏障(blood brain barrier，BBB)受损，血管通透性增加，毛细血管内血浆蛋白与水分渗出，脑组织内液体异常聚积；