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- Abnormality of 5-hydroxytryptamine (5-HT) signaling system leads to abnormal gastrointestinal motility, secretion and visceral hypersensitivity. 5-羟色胺(5-HT)信号系统异常可致胃肠动力、分泌功能异常和内脏高敏感性,与多种功能性胃肠病密切相关。
- Results: Both of TNBS and CI induced visceral hypersensitivity successfully,but the degree and concomitant pathological changes were significant difference. 结果:两种方法制作的动物模型均能复制成功,但模型的程度及伴随病理性改变等具有差异。
- Several studies showed that the attack of IBS might be related to the gastrointestinal motility, visceral hypersensitivity, infection of the bowel and several other factors. 研究显示IBS可能与肠道动力、内脏感觉过敏和肠道感染等因素有关。
- Objective To investigate the effects of N-methyl-D-aspartate receptor (NMDAR) in the spinal dorsal horn in visceral hypersensitivity in rats with colonic inflammation. 目的:通过观察大鼠结肠炎不同时期脊髓背角N-甲基-D-天冬氨酸受体(NMDAR)的表达,探讨突触后NMDAR在内脏高敏感性中的作用。
- Objective To study the mechanism of visceral hypersensitivity in patients with irritable bowel syndrome (IBS) and get further evidence in alterations of intestinal afferent pathways by cerebral evoked potentials(CEP). 目的 通过记录并比较直肠扩张脑诱发电位 (CEP)的特征及饮冰水后CEP的改变 ,探讨肠易激综合征 (IBS)患者内脏高敏感性的发生机制 ,旨在进一步获得IBS感觉传入通路异常的客观依据。
- Conclusion The ultrastructural changes of chalice cell, plasma cell, neuroendocrine cell and mast cell may have a potential effect on neuro-immunologic mechanism and visceral hypersensitivity of IBS. 结论小肠和结肠黏膜内杯状细胞、浆细胞、神经内分泌细胞、肥大细胞等超微结构的改变,可能在IBS症状发生的神经免疫、内脏感觉过敏等机制中有一定的作用。
- Oesophageal visceral hypersensitivity 食管内脏高敏感
- Study on the pathogenesis of oesophageal visceral hypersensitivity 食管内脏高敏感机制的研究
- Visceral hypersensitivity model induced by intraperitoneal injection of chicken egg albumin 腹腔注射卵清白蛋白致大鼠内脏高敏感的研究
- Study of peripheral and central mechanism of visceral hypersensitivity in non - erosive reflux disease patients 非糜烂性反流病内脏高敏感的外周与中枢机制研究
- Application of visceral hypersensitivity to functional gastrointestinal disorders 内脏高敏感与功能性胃肠病
- Keywords Irritable bowel syndrome;Cerebral evoked potentials;Rectal distension;Visceral hypersensitivity; 肠易激综合征;脑诱发电位;直肠扩张;内脏高敏感性;
- Keywords visceral hypersensitivity;serotonin;enterochromaffin cell;mast cell;irritable bowel syndrome; 内脏高敏感;5-羟色胺;肠嗜铬细胞;肥大细胞;肠易激综合征;
- Keywords Oesophageal visceral hypersensitivity;Non-erosive reflux disease;Functional heartburn;Pathogenesis; 食管内脏高敏感;非糜烂性反流病;功能性烧心;发病机制;
- Keywords Butyrate;Visceral hypersensitivity;Colorectal distention;Rapid eye movement sleep deprivation; 丁酸钠;内脏感觉过敏;结直肠扩张;快动眼睡眠剥夺;
- Visceral hypersensitivity and the change of serum corticosterone level after colorectal distention in anxiety rats and their significance 焦虑大鼠内脏敏感性增高以及行直结肠扩张后血清皮质酮的变化及意义
- Keywords Serotonin Transporter;5-hydroxytryptamine;Visceral Hypersensitivity;Irritable Bowel Syndrome;Drug Therapy (TCD); 羟色胺转运体;5-羟色胺;内脏高敏感;肠易激综合征;中药疗法;
- Objective To identify the features of colon electricity activities and the motion in viscerally hypersensitive rats. 摘要目的探讨内脏高敏感大鼠结肠电活动及运动的特点。
- Conclusion There are significant differences between the control group and the model group in electricity and motion of viscerally hypersensitive rat. 结论内脏高敏感大鼠结肠电活动及运动有明显异常。
- Visceral hypersensitivity 内脏高敏感性