While the endothelial cells were cultured in the media containing CGRP,the expression of ICAM-1 significantly diminished and the expression of NOS and TIMP-2 raised,especially in ECs induced by diamide.

• 当 CGRP 作用于正常内皮细胞和联胺诱导后的内皮细胞,对 ICAM-1的表达有明显的下调作用,对 NOS 和 TIMP-2的表达则有明显的上调作用。