Without obvious influence in brain metabolic functions,L1 KO mice is an useful animal model for investigation of the role of L1 in brain ischemia.

• L1CAM基因缺失对小鼠脑局部代谢功能无明显影响,提示L1 KO小鼠可作为研究L1CAM在脑缺血中作用的动物模型。