X-box binding protein 1 (XBP1), as a transcription factor of unfolded protein response (UPR), is found to be closely related with protein folding in endoplasmic reticulum (ER).

• 研究发现X-盒结合蛋白1(X-box binding protein1,XBP1)与内质网中蛋白质的折叠密切相关,参与调控未折叠蛋白的折叠、修饰、分选与包装;