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- 目的 建立携带人类淀粉样前体蛋白瑞典型突变 (Swedish mutation of amyloid precursorprotein,APPSWE)基因的转基因小鼠模型。Objective To prepare transgenic mice model of human (Swedish mutation of amyloid precursor protein, APP SWE ) gene. Methods By pronuclear microinjection, human APP SWE genes were microinjected into pronuclei of zygotes of C57 and Kunming white mice.
- 目的 确认淀粉样纤维蛋白基因 (amyloid fibrils,BRI)基因在 1对同源但转移能力不同的肺腺癌细胞系 AGZY83- a和 Anip973中的序列并分析其表达。Objective To investigate the sequence of amyloid fibrils (BRI) gene and its expression in two lung adenocarcinoma cell lines AGZY83-a and Anip973 with the same tumor origin but different metastatic potential.
