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- To predict antigen epitopes on B cell of VP2 of canine parvovirus 2b subtype(CPV-2b),the VP2 gene of CPV-2b was cloned and sequenced. 对犬细小病毒2b亚型衣壳蛋白VP2基因进行了克隆、测序,并用分子生物学软件DNAStar对VP2基因的推导氨基酸序列进行了表位分析。
- Objective:To approve there are commen antigen epitopes and cross-reaction lying between oilseed rape(Brassica campestris L. 目的:证实油菜花粉和蒿草花粉存在共同抗原决定簇和交叉反应。
- The antigenic epitopes recognized by WM53 are located in the AAR 17-60 of CD33 antigen. The antigenic epitopes recognized by M195 are located in the AAR 170-262 of CD33 antigen. 结论HIM3-4、WM53、M195识别的CD33抗原表位分别位于115~170、17~60、170~262氨基酸。
- Seven Moth recognized different antigen epitopes of AIF from different tissues, butMcAb 5c3 and 4d2 recognized the same antigen epitope of AIF. 抗AIFMcAbs均与各自AIF分子上不同抗原决定簇结合,其中针对不同组织AIF的McAb5c3和4e2作用于同一抗原决定簇。
- Because the exact antigenic epitopes responsible for immunity are not well understood, whole-cell vaccines are best. 因为还不清楚决定免疫力的具体抗原决定部位,所以全细胞疫苗是最好的。
- By the host machinery,the glycosylation of these proteins protect potential protein antigenic epitopes on the virus. 它使病毒粒子具有高度糖基化的表面,帮助HIV逃避人体免疫细胞识别和攻击。
- Prokaryotic expression of structural domains of the Newcastle disease virus fusion protein and analyses of their antigenic epitopes. 新城疫病毒F蛋白结构域基因原核表达与抗原表位分析
- Seven synthesized peptides were produced by mimicking the antigenic epitopes of the S-protein in SARS-CoV with computer techniques. 利用计算机技术模拟SARS冠状病毒S蛋白的抗原表位并合成了7条多肽,研究合成肽与SARS患者早期血清的反应性。
- Results:The new gene encoding the antigen epitope of SARS-CoV S protein was designed and synthesized s... 结论:可以重新设计新基因产生新型候选重组疫苗。
- Ke Shen, et al. Bio-panning of HGV antigen epitope from a phage display library. Progress in Natural Science. 2000;10(6):446-450. 柯屾,等。核糖体展示技术。见:分子文库-中国生物技术丛书。沈倍奋主编。2001。北京:科学出版社。
- It was demonstrated that the cDNAs coding to S. japonicum antigen epitope peptide could be inserted successively into vector plasmid. 结果单个抗原表位或两个不同的表位编码基因被成功地插入真核表达载体。
- Conclusion: 1.The prediction of antigen epitope is accurate. High titer antibodies of anti-GPBB were obtained with the compound peptide immuning animals. 结论:1.本文以多参数预测的抗原表位比较准确,以此为根据合成的复合肽抗原免疫动物制备了高效价的抗体,抗体即可与天然抗原反应,也具有高度的特异性。
- Objective:To design a new gene encoding the antigen epitope of the spike protein(S protein) of severe acute respiratory syndrome coronavirus (SARS-CoV) and express the new gene. 目的:表达严重急性呼吸综合征(SARS)冠状病毒S蛋白的抗原表位序列,为研制新型的SARS病毒疫苗提供新思路。
- Objective To obtain the antigenic epitopes which can affinitive bind to theHCV(hepatitis c virus) polyclonal antibodies by using a phage 12-mer peptide libraryand to test the efficiency of converse biopannning by using negative serum. 目的筛选噬菌体展示随机12 肽库中可以与HCV 抗体阳性的血清特异性结合的序列,在HCV 表达的蛋白分子上找到这个抗原表位, 分析其序列、结构特点与功能的关系。 同时检验用阴性血清逆向筛选是否能提高筛选效率。
- The expressed fusion proteins could be recognized by antibodies of rabbit anti RESA peptide EENVEHDA by Western blotting,indicating that the fusion proteins harbored the antigenic epitopes of Plasmodium falciparum . 免疫印迹分析显示表达产物可与兔抗恶性疟原虫RESA多肽抗原的抗体发生特异性免疫反应,提示融合蛋白中含有恶性疟原虫抗原位点。
- Two fusions genes, CTB/ATE and CTB/AWTE, which contain sequences coding for multiple antigenic epitopes of malaria Plasmodium falciparum and cholera toxin B subunit (CTB) gene used as a carrier were constructed. 以霍乱毒素B亚基(CTB)基因为载体,构建了含不同抗原表位的恶性疟原虫的融合基因CTB/ATE和CTB/AWTE。
- Our results suggest that MBP and PLP might play some important role in initiating demyelinating diseases, and that M87-106, P40-60, P95-117 and P185-206 might be candidates for antigen epitope relevant to MS. 作为神经髓鞘主要成分的 MBP和 PLP免疫反应性高 ,可能在体内触发自身免疫反应过程发挥作用 ,而 M87-1 0 6、P40 -60、P95 -1 1 7和 P1 85 -2 0 6等位点值得进一步研究。
- Both of the common methods of experimental determination and theorical prediction for identifying T cell antigen epitope and the methods of T cell epitope analysis were summarized. 综述了近年来实验确定和理论预测T细胞蛋白质抗原表位的常用方法,以及T细胞抗原表位分析的研究方法。
- The attraction between an antigen and an antibody. 化合力抗原和抗体之间的相互吸引
- Peptide of HBV surface antigen epitope 乙型肝炎表面抗原表位肽