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- Methods:Cetirizine dihydrochloride were synthesized from piperazine hexahydrate and4-chlorobenzyl chloride by six steps reactions. 方法 :对关键的缩合反应进行了改进 ,以六水哌嗪和对氯氯苄为原料 ,经六步反应得到产品。
- Cetirizine dihydrochloride, as the second generation H1-receptor antagonist, is one of the best-selling anti-allergy drugs all over the world. 摘要盐酸西替利嗪是第二代H1受体拮抗剂,是目前国际上最畅销的抗过敏药物之一。
- Cetirizine dihydrochloride,as the second generation H1-receptor antagonist,is one of the best-selling anti-allergy drugs all over the world. 盐酸西替利嗪是第二代H1受体拮抗剂,是目前国际上最畅销的抗过敏药物之一。
- In this paper,the medication safety,efficacy and the latest clinical application of cetirizine dihydrochloride are introduced in brief. 介绍了盐酸西替利嗪的安全性、疗效、最新的临床应用;
- Keywords cetirizine dihydrochloride;enantioselection;achiral-chiral chromatography; 盐酸西替利嗪;立体选择性;非手性-手性色谱;
- Keywords Cetirizine dihydrochloride;Zytec;Chromatography;high pressure liquid;Biological avoilability; 盐酸西替利嗪片;仙特明;色谱法;高压液相;生物利用度;
- cetirizine dihydrochloride 二盐酸西替利嗪
- The resultant hydrolytic reaction product is dihydrochloride. 所形成的水解反应物是二盐酸。
- OBJECTIVE To improve the synthesis of cetirizine dihydrochlorride. 目的改进盐酸西替利嗪的合成工艺。
- The resultant hydrolytic reaction product is methylenedioxyamine dihydrochloride. 所形成的水解反应物是二盐酸甲撑二氧胺。
- The discretion of oral open Ruitan, cetirizine, diphenhydramine, such as antihistamines cyproheptadine of. 可酌情口服开瑞坦、西替利嗪、苯海拉明、赛庚啶等抗组胺药物。
- Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation,hydrogenation,cyclization with an overall yield of 8.05%. 以苯甲酰氯为原料;经酰化;还原;环合等反应合成左旋西替利嗪盐酸盐;反应总收率为8.;05%25。
- There are reports of cetirizine by 3 weeks after treatment, pathology of eosinophils by 75%. 有报告用西替利嗪治疗3周后,病理中嗜酸性粒细胞减少75%25。
- The results indicate that arte- sunate is significantly superior to quinine dihydrochloride in both aspects. 结果表明,青蒿琥酯的杀虫速度比二盐酸奎宁快,治愈效果优于二盐酸奎宁。
- CONCLUSION The research indicated that cetirizine is an anti-allergic H1 receptor antagonist with high efficacy. 结论 盐酸西替利嗪是一个具有抗过敏、高效、速效的H1受体阻断药。
- The interaction of hematoporphyrin dihydrochloride(HD) with DNA was studied by using neutral red(NR) as a probe. 以中性红(NR)作探针研究了血卟啉(HD)与DNA的相互作用。
- Conclusion The cetirizine united the desloratidineis more effect than take with the desloratidine group. 结论西替利嗪联合地氯雷他治疗慢性荨麻疹疗效较单用地氯雷他定治疗有明显提高。
- OBJECTIVE To prepare cetirizine gel and establish a quality control method for the gel. 目的:制备西替利嗪凝胶剂,并建立质量控制方法。
- Methods The nitrite was detected from samples by N-Naphthylethylenediamine Dihydrochloride. 方法用盐酸萘乙二胺法检测样品中的亚硝酸盐。
- The currently approved drug in the US, melarsomine dihydrochloride, is marketed under the brand name Immiticide. 目前已经获批的药物有砒霜。