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- OBJECTIVE To improve the synthesis of cetirizine dihydrochlorride. 目的改进盐酸西替利嗪的合成工艺。
- cetirizine dihydrochlorride 盐酸西替利嗪
- The discretion of oral open Ruitan, cetirizine, diphenhydramine, such as antihistamines cyproheptadine of. 可酌情口服开瑞坦、西替利嗪、苯海拉明、赛庚啶等抗组胺药物。
- There are reports of cetirizine by 3 weeks after treatment, pathology of eosinophils by 75%. 有报告用西替利嗪治疗3周后，病理中嗜酸性粒细胞减少75%25。
- CONCLUSION The research indicated that cetirizine is an anti-allergic H1 receptor antagonist with high efficacy. 结论 盐酸西替利嗪是一个具有抗过敏、高效、速效的H1受体阻断药。
- Conclusion The cetirizine united the desloratidineis more effect than take with the desloratidine group. 结论西替利嗪联合地氯雷他治疗慢性荨麻疹疗效较单用地氯雷他定治疗有明显提高。
- OBJECTIVE To prepare cetirizine gel and establish a quality control method for the gel. 目的:制备西替利嗪凝胶剂,并建立质量控制方法。
- A group(42 cased) took Cetirizine orally 1piece(10mg) and was injected with BCG-PSN 0.5mg(1 branch) ,every 2d for 1 dose. 治疗组(42例);患者每日口服西替利嗪l片(10mg);且肌肉注射卡介菌多糖核酸注射液l次/2d;0.;5mg(1支)/次;
- Objective To investigate and compare the effect and safety of levocetirizine and cetirizine for the treatment of chronic idiopathetic urticaria (CIU). 目的研究和比较左西替利嗪和西替利嗪治疗慢性荨麻疹的疗效和安全性。
- The results showed that cetirizine significantly inhibited PCA in rats, and effectively reduced the contraction of the uterus in Schultz-Dale reaction. 结果表明：西替利嗪对大鼠同种被动皮肤过敏反应有显著的抑制作用，大中小三组间有明显的量效关系，大中剂量组的作用优于扑尔敏，小剂量组与扑尔敏作用相当。
- Methods:Cetirizine dihydrochloride were synthesized from piperazine hexahydrate and4-chlorobenzyl chloride by six steps reactions. 方法 :对关键的缩合反应进行了改进 ,以六水哌嗪和对氯氯苄为原料 ,经六步反应得到产品。
- Cetirizine decreased the number of histamine induced shock in guinea pig, prolonged the delitescence period of histamine induced asthma (P＜0.05). 也能明显的抑制组胺对豚鼠引起的休克作用，使组胺所致的豚鼠哮喘潜伏期明显延长(P＜0.;05)。
- Cetirizine dihydrochloride, as the second generation H1-receptor antagonist, is one of the best-selling anti-allergy drugs all over the world. 摘要盐酸西替利嗪是第二代H1受体拮抗剂，是目前国际上最畅销的抗过敏药物之一。
- The median duration of wheal inhibition of at least 70% was zero with placebo and desloratadine and was 21.9 hours with cetirizine (P <.001). 使用安慰剂和地氯雷他定过程中，至少70%25风团抑制持续期的的中位数是0，西替立嗪则为21.;9小时(P <
- The amounts of three excipients that had significant influence on viscosity of cetirizine hydrochloride cataplasm were investigated. 考察了对盐酸西替利嗪巴布剂黏性影响较重要的3个辅料的用量,并研究了优化处方的含水量、黏性及体外释放度的关系。
- Objective To study improved synthetic method of 1-[(4-chlorophenyl)phenylmethyl]-piperazine, the intermediate of cetirizine hydrochloride. 目的探讨西替利嗪的中间体1-犤(4-氯苯基)苯甲基犦-哌嗪的合成方法的改进。
- Objective: To study the pharmacokinetics and relative bioavailability of domestic cetirizine hydrochloride tablet in healthy volunteers. 目的：研究国产盐酸西替利嗪片的人体药代动力学和相对生物利用度。
- Cetirizine dihydrochloride,as the second generation H1-receptor antagonist,is one of the best-selling anti-allergy drugs all over the world. 盐酸西替利嗪是第二代H1受体拮抗剂,是目前国际上最畅销的抗过敏药物之一。
- In this paper,the medication safety,efficacy and the latest clinical application of cetirizine dihydrochloride are introduced in brief. 介绍了盐酸西替利嗪的安全性、疗效、最新的临床应用;
- OBJECTIVE Improving traditional synthesis method of Cetirizine Hydrochloride to optimize industrial production technique. 目的改进文献合成西替利嗪的方法,优化工业生产。
