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In addition,the hypemethylaty within DNA maybe leads to the inactivation of DLC-1 of the colorectal cancer cell line sw480. 结论:DLC-1基因可影响结肠癌细胞sw480的增殖能力和侵袭力,并使结肠癌细胞sw480细胞周期阻滞于G2期,DNA甲基化可能是导致DLC-1在sw480细胞中的失活的一个重要原因。
CAPE can inhibit the proliferation of colorectal cancer cell line SW480, and the mechanism is related to arrest the cell cycle G 1 and induce cell apoptosis. CAPE对大肠癌SW 4 80细胞株具有明显的生长抑制作用 ,其作用机制与阻滞细胞周期G1期和诱导细胞凋亡有关。
Objective:To investigate the expression of DLC-1 in the colorectal cancer cell line sw480.Methods:DLC-1 mRNA and protein expression was studied in the colorectal cancer cell line CaCo2 and sw480 using RT-PCR and Western blot. 目的:初步探讨DLC-1基因在结肠癌细胞sw480中的表达改变及其可能机制; 方法:采用RT-PCR和Western blot分析结肠癌细胞CaCo2、sw480的DLC-1表达情况;
Massari D, Trobonjac Z, Rukavina D, et al. SMS 201-995 enhances S-phase block induced by 5-fluorouracil in a human colorectal cancer cell line[J]. Anticancer Drugs, 2005, 16(9):989-996. 吴佩;闫竞一;茆家定;等.;胃泌素、生长抑素对大肠癌细胞周期的调控作用[J]
The protein expression of PTEN was detected in three colorectal cancer cell lines with different metastasic ability by western blot. (2 )利用Westernblot法检测不同转移潜能的大肠癌细胞系内PTEN蛋白的表达水平 ,说明PTEN蛋白的表达对大肠癌细胞转移潜能的影响。
Objective To observe the effect of caffeic acid phenethyl ester (CAPE) on proliferation, cell cycle and apoptosis of human colorectal cancer cell line SW480.MethodsSW480 cells were treated with CAPE . 目的探讨咖啡酸苯乙酯(caffeic acid phenethyl ester,CAPE)对培养的大肠癌SW480细胞增殖、细胞周期和细胞凋亡的影响。
Human colorectal cancer cell line 结肠癌细胞株
CT-26 colorectal cancer cell line CT-26结直肠癌细胞株
colorectal cancer cell lines SW480 结直肠癌细胞株SW480
Effect of 5-Aza-CdR on DLC-1 expression and proliferation of human colorectal cancer cell line HT29 5氮杂胞苷对HT29细胞DLC-1基因表达和细胞增殖活性的影响
Expression of Tumor Suppress Gene DLC-1 in the Colorectal Cancer Cell Line Sw480 抑癌基因DLC-1在结肠癌细胞sw480中表达的研究
Keywords Celecoxib;Colorectal cancer cell line;Signal transduction;Cell apoptosis;Cytochrome C; 塞来昔布;大肠癌细胞株;信号转导;细胞凋亡;细胞色素C;
The effects of paeonol on inhibiting the proliferation of human colorectal cancer cell line HT-29 and its molecule mechanism 丹皮酚对大肠癌HT-29细胞的增殖抑制作用及其机制的探讨
The effect of caffeic acid phenethyl ester (CAPE) on proliferation and cell cycle in the colorectal cancer cell line SW480 咖啡酸苯乙酯对大肠癌SW480细胞生长和周期的影响
Inhibitory effects of EGFR antisense oligodeoxynucleotide with liposome in human colorectal cancer cell line 吴金生,何勇, 腹腔内化疗治疗消化系癌49例黄维坤,司娜,顾琦,孙新平,崔惠强,杨旭凯,南小东
Construction of a Model Used for the Mismatch Repair Functional Analysis in vitro and Being Used in the Human Colorectal Cancer Cell Line and Tumor Tissue 构建体外错配修复功能分析模型及其在人类结直肠癌细胞株及肿瘤组织中的应用
colorectal cancer cell line 肠癌细胞系
Laboratory studies show CMV can disrupt cellular processes with potential to promote malignant growth, particularly affecting colorectal cancer cell development. 实验室研究显示,CMV能打断细胞程序,潜在性促进恶性生长,特别影响结肠直肠癌细胞的发展。
Aim:To study the genetic instability of BGC 823 gastric cancer cell line. 目的 :研究人胃癌BGC 82 3细胞系的遗传不稳定性。
Results The results showed that the colorectal cancer cells had swollen and vacuolated mitochondria with disarrangement and unfolding of cristae. 结果：直结肠癌细胞线粒体肿胀，空泡化，脊稀少，排列紊乱。