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DD genotype and D allele is closely related to IR and abnormal plasm lipid metabolism,but I allele is not. ACE基因DD型和D等位基因与IR及血脂代谢异常有关 ,与I等位基因则无关
However,the DD genotype and D allele had higher frequency in NIDDM with retinopathy than without. DD 型与D 等位基因在DR（＋）组出现频率高，DR（＋）组与DR（－）组相比，基因型及等位基因分布差异具显著性。
The frequency of D allele genotype in ISR group (51.7%) was far higher than that of non-ISR group (28.8%). 卡方检验结果显示再狭窄组D等位基因频率(51.;7%25)明显高于未狭窄组D等位基因频率(28
Results The frequencies of DD genotype and D allele in patients with AMI were higher than those without AMI (P<0.01). 结果血管紧张素转换酶基因型分布及等位基因频率在病例组及对照组间差异有显著性(P<0.;01)。
The frequencies of frequencies of the ACE D allele in EHT groups of were hig her than that in the health controls, respectively (P<0.05). EHT组ACE I/ D基因多态性等位基因频率 I为 0 .;50;D为 0
The frequencies of the DD genetype and the D allele in Kidney Yang asthenia were significantly higher than in Kidney Yin asthenia (P<0 01 or P<0 05) . 且肾阳虚证DD型频率与D等位基因携带率明显高于肾阳虚证 (P <0 0 5 )。
DD genotype of ACE gene in Uighurs was 25.9%,DI genotype was 48.1% and II genotype was 25.9%. Allele frequencies were 0.05 for the D allele and 0.50 for the I allele. 所有被调查的 81例健康维吾尔族人ACE基因中 ,DD型占2 5 9%25,DI型占 48 1%25,II型占 2 5 9%25,D与I等位基因出现频率均为 0 5 0。
The frequencies of DD genotype(60%) and D allele(74 29%) were significantly higher in the MI group than those in the healthy subjects(29 17% and 51 05%, P <0 05). 老年心肌梗死组 ACE基因中缺失型 (DD型 )分布 (60%25 )明显高于正常对照组 (2 9.;1 7%25 ) (P<0
Conclusions Serum ACE level was associated with ACE gene I/D polymorphism.It suggests that D allele might be a genetic risk factor for stroke in the elderly. 结论血浆ACE水平和ACE基因多态性有关，提示D等位基因可能与老年脑卒中的危险因素有关。
Conclusion Perindopril has effects on regression of the endothelial dysfunction of brachial artery in elderly hypertensive patients, especially in those with the D allele. 结论培垛普利能逆转老年高血压患者的肱动脉内皮依赖舒张功能障碍，含有D等位基因的患者获益更大。
DD genotype and D allele showed obvious dominance in drug-resistant group and cases performed with renal biopsy,especially those with focal segmental glomerular sclerosis(FSGS). 耐药组和肾活检病例尤其局灶性节段性肾小球硬化 (FSGS)明显显示缺失型 (DD基因型 )和D等位基因占优势 ,临床耐药的肾活检病例也以DD型和D等位基因明显占优势。
Results 48.3% of patients were homozygous for DD(P<0.05,odds ratio [OR] 2.04); and only 8.6% of patients carried the II genotype(OR 0.34). Patients had a significantly higher D allele frequency(P<0.01,OR 1.9)than did the control. 结果子痫前期组ACEDD型占48.;3%25(P<0
Results: (1) The DD genotype and D allele were significantly more common in diabetic patients with carotid atherosclerosis than in those without it (Frequencies of DD genotype: 0.50 vs 0.18; frequencies of D allele: 0.71 vs 0.38; P < 0.01 ). 结果 :(1)糖尿病颈动脉硬化性病变组ACE基因DD型和D等位基因频率显著高于无颈动脉硬化性病变组 (DD基因型频率 :0 .;5 0vs 0
SLE had higher frequency of ACE DD genotype and D allele than that of normal controls, SLE group with clinical renal lesion also had higher frequency of ACE DD genotype and D allele than the SLE group without clinical renal lesion. ACE基因DD型和D等位基因分布频率SLE组明显高于正常对照组，临床有肾脏受累表现的SLE组明显高于临床无肾脏受累表现的SLE组。
The frequencies of II, ID and DD genotype of ACE in lung cancer group were 0.447, 0.447 and 0.106 respectively, and the frequencies of I and D allele were 0.670 and 0.330 respectively. 肺癌组中II、ID和DD基因型频率分别为0.;447、0
The frequency of D allele gene(0.75) and the percentage of ACE DD genotype(65%) were significantly higher in PIH patients than the frequency(0.32) and the percentage(16%) in the control population(P<0.01). 观察组的缺失型纯合子 (DD型 ) ACE基因占 6 5%25 ;高于对照组的 16%25 ; 观察组的缺失型 (D型 ) ACE等位基因出现频率为 75%25 ;亦高于对照组的 33%25 (P<0 .;0 1)。
P = 0.047 within GNB3 CC+CT genotype. The results suggest that ACE, or a nearby gene, is a male-specific susceptible gene for hypertension, and that there may exist epistatic gene-gene interaction between ACE D allele and GNB3 825C allele. P=0.;047
The DD genotype frequency(0.64) was higher in BD group than in hypertension group (0.31, P <0.01) and the normal controls (0.17, P <0.01), and D allele gene was higher than the hypertension group and the normal controls ( P <0 01). BD组 DD型基因频率为 0 .;6 4;高于高血压病组的 0
There were no significant effects on hypertension either COC or Dallele(P >0. 05) ,but if the women with D allele had a history of using COC for more than 15 years, the risk of hypertension would be significantly high (OR = 5.71, P = 0.03). 无论是单独考虑服药或是单独考虑携带D型等位基因;其对高血压均没有显著性影响(P>0.;05)。但是携带D型等位基因的妇女;如果同时服药15年以上;发生高血压的危险性将有显著性增加(OR=5
If I had my way, I'd go to the movies tonight. 假如我做得到的话，我今晚会去看电影。