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- The labelled perlolyrine was suitable for studying drug metabolism. 结果表明,合成的氘标川芎哚满足药物代谢研究的需要。
- Liver is the main organ for drug metabolism, it nearly have all UGT isozymes. 肝脏是葡醛酸缀合反应的主要场所，几乎含有所有的UGT同工酶。
- Drug metabolism is very deficient qualitatively and quantitatively in the newborn. 新生儿对药物的代谢，无论在质量和数量上都非常不足。
- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Because of the importance of UGTs in drug metabolism in humans, the identifications of key UGT enzymes are very important. 由于UGT酶在人类药物代谢方面的重要性,对关键UGT酶的鉴定是十分重要的,需要引起人们日益的重视。
- Moreover, physicians are unsure how to apply the drug metabolism information from pharmacogenomics tests in their prescribing decisions. 同时，医生也不确定如何将药物基因组学中经由测试所得到的药物代谢资讯，应用到诊断中。
- Results Varied genes related to drug metabolism have SNP phenomenon, which are closely associated with interindividual diversity in drug response. 结果 多种药物代谢相关基因存在SNP现象，且与药物效应个体多样性有着密切联系。
- Predicting of drug metabolism in humans based on animal experiments is complicated by species differences in the catalytic properties of these enzymes. 根据动物实验来预测人体的药物代谢时,代谢酶的种属差异性会使这项研究工作变得非常困难。
- Drug Metabolism and Toxicology Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria. 哈尔滨医科大学,药理学教研室,黑龙江,哈尔滨,150081
- Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity. 摘要药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起著重要的作用，对组织器官的药物效应和毒性的易感性产生重要影响。
- It was sug-gested that Bama miniature pigs and Guizhou miniature pigs were both feasible for experimental animal model for evaluat-ing drug metabolism in some degree. 提示巴马香猪、贵州小型香猪作为药物评价的实验动物具有一定可行性。
- The main tasks for post-doctoral fellow include research in pharmacokinetics and clinical pharmacology, especially in drug metabolism, pharmacokinetics, and pharmacogenetics. 主要开展药物代谢（药物相互作用）以及遗传药理学与药物基因组学方面的研究工作。
- Drug metabolism enzymes(DME) play a significant role in drug detoxification and activation,which exert important effect on drug efficacy and sensitivity to toxicity. 药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用,对组织器官的药物效应和毒性的易感性产生重要影响。
- Objective: To promote the study of drug metabolic enzymes in clinical practice. 目的:为了促进药物代谢酶在临床上的深入研究。
- The genetic variations of drug related proteins including drug metabolism enzymes,drug transport proteins,and drug active receptors and/or targets are basic factors resulting in individual and ethnic differences in drug response. 除环境因素外,药物代谢酶、药物转运蛋白以及药物作用受体或靶位等药物反应相关蛋白的基因变异是引起药物反应个体差异和种族差异的根本原因。
- This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy. 本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
- With the advanced progress of mononucleotide sequencing polymorphism using genomics, the variable expression of individual genes may be related to the drug metabolism and bioavailability. 随着基因组学对单核苷酸序列多态性的研究进展，越来越多的研究表明，个体基因水平的差异与药物代谢和生物利用度密切相关。
- A candidate is expected to have a good GLP and regulatory understanding, knowledge of pharmacokinetics and drug metabolism in drug research and development, and good computer skills. 最好了解GLP及其相关规定;并在药物的药代动力学方面有所研究和学习; 良好的计算机使用技能.
- The nurse diluted the drug with saline water. 护士用生理盐水把药加以稀释。
- Drug metabolism determines several pharmacological and toxicological properties of pharmaceuticals and is catalyzed by drug metabolizing enzymes. 药物代谢是在代谢酶催化下完成的,它决定着药物的药理学和毒理学特性。
