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- OBJECTIVE To prepare Tandospirone citrate(TDS) osmotic pump tablets and investigate the factors influencing the drug release profile in vitro and drug release mechanism. 目的制备枸橼酸坦度螺酮(TDS)渗透泵型控释片,考察影响其释药行为的因素,并探讨释药机理。
- Keywords vincritine sulfate;mitoxantrone chlorhydric acid;liposome;drug release profile in vitro;biodistribution; 盐酸米托蒽醌;硫酸长春新碱;脂质体;体外释放;体内分布;
- drug release profile in vitro 体外释放
- Keywords 8-methoxypsoralen;liposomal gel;drug release profiles in vitro; 甲氧沙林;脂质体凝胶;体外释药动力学;
- ABSTRACT Objective To prepare capreomycin sulfate liposomes to develop a method for determining its drug content and entrapment efficiency and to study the release profile in vitro. 目的制备硫酸卷曲霉素脂质体,建立含量和包封率的测定方法,初步考察其体外释放规律。
- Objective To prepare the sustained-release tablets of tiopronin and investigate the release profile in vitro of the sustained-release tablets. 目的 制备硫普罗宁缓释片并对其体外释放度进行考察。
- OBJECTIVE To prepare hydroxycamptothecinsemisolid lipid nanoparticles(HCPT-SSLN) and study the release profile in vitro. 目的:制备羟基喜树碱的半固体脂质纳米粒(HCPT-SSLN),初步考察其体外释药规律。
- Accelerated release testing could be applied to evaluate the drug release profile of huperzineA PLGA microspheres. 加速释放度试验可用于快速评价石杉碱甲微球的释药特性。
- Microsphere size, which has a significant effect on drug release rate, can potentially be aried to design a controlled drug deliery system with desired release profile. 微球大小对药物释放率有很重要的影响,人们认为可以改变其大小以建立一个药物释放符合需要能够控制药物释放的体系。
- Objective To prepare colchicine sustained-release pellets and investigate the drug release mechanism in vitro. 目的 制备秋水仙碱缓释微丸,并对其体外释药规律进行考察。
- Objective: To prepare nefopam hydrochloride sustained-release tablets and investigate the drug release in vitro. 目的:研制盐酸奈福泮缓释片,并考察其体外释放度。
- Objective To prepare paracetamol sustained-release pellets and investigate the drug release mechanism in vitro. 目的制备扑热息痛缓释微丸,并对其体外释药情况进行研究。
- OBJECTIVE To prepare thymopentin microspheres and investigate the drug release in vitro. 目的制备胸腺五肽微球并对其体外释放进行考察。
- OBJECTIVE To study the drug release mechanism of helicid(HD) bioadhesive sustained-release tablet and to determine the adhesive force in vitro. 目的研究生物黏附性神衰果素缓释片的体外释放度及释药规律,并测定其体外黏附力。
- OBJECTIVE To evaluate drug release properties in vitro of the hydrogel films made of cross-linked hyaluronic acid derivatives. 目的对交联透明质酸衍生物制备的载药水凝胶膜进行体外药物释放研究。
- OBJECTIVE To study the preparation process,asssy and in vitro drug release of temozolomide polylactic-co-glycolic acid microspheres. 目的:对替莫唑胺聚乳酸-羟基醋酸微球的制备工艺、含量测定及体外释药特性进行初步研究。
- OBJECTIVE To prepare clindamycin hydrochloride microcapsule by means of intra liquid desiccation and to determine its in vitro drug release. 目的采用液中干燥法制备盐酸克林霉素微囊,并考察其体外释药特性。
- Objective To prepare docetaxel nanostructured lipid carriers (Docetaxel-NLC) and investigate their pharmaceutical properties and their in vitro drug release behavior. 目的 制备多西他赛纳米脂质载体,并考察其剂型性质及体外释药行为。
- Methods Gelatin microspheres containing diclofenac sodium were prepared by simple coacervation technique and the drug release in vitro and vivo were tested. 方法采用单凝聚法制备双氯芬酸钠明胶微球,并对微球的体内外释药进行考察。
- OBJECTIVE To prepare enteric microspheres containing thymosin, and evaluate its in vitro release profiles and in vivo bioactivity. 目的制备胸腺肽肠溶微球,并对其体外释药特性及调节免疫的体内活性进行评价。