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- Pharmacogenomics is defined as the study of the association between genetics and drug response. 药物基因组学是研究遗传学与药物反应的相互关系。
- Results Varied genes related to drug metabolism have SNP phenomenon, which are closely associated with interindividual diversity in drug response. 结果 多种药物代谢相关基因存在SNP现象,且与药物效应个体多样性有着密切联系。
- With the exception of drug metabolizing enzymes, drug receptors are another important kinds of proteins involved in drug response. 这些差异的产生是遗传因素与环境因素共同作用的结果,其中遗传因素为决定性因素。
- Such information is changing the understanding of how genetics influences disease development and drug response, and contributing to the discovery of new treatments. 这些信息改变着人们对基因是如何影响疾病发展和药物反应的认识,有助于新疗法的开发。
- Pharmacogenomics essentially promote the development of personalized medicine by focus on the influence of human inherited polymorphism to the drug response. 发现药物基因组学作为功能基因组学在医药学中的应用,能通过对基因多态性的研究,从根本上促进个体化用药的发展。
- Researchers are encouraged to publish results based on combining HapMap data with data from other projects, particularly in efforts to find genes affecting a disease or a drug response. 鼓励研究者发表对HapMap数据和其他研究计划的数据结合分析的文章,尤其是致力于寻找影响疾病或药物应答的基因。
- The genetic variations of drug related proteins including drug metabolism enzymes,drug transport proteins,and drug active receptors and/or targets are basic factors resulting in individual and ethnic differences in drug response. 除环境因素外,药物代谢酶、药物转运蛋白以及药物作用受体或靶位等药物反应相关蛋白的基因变异是引起药物反应个体差异和种族差异的根本原因。
- Our results do not support a role of the HCRTR2 G1246A polymorphism in drug responses in CH. 我们的研究结果认为食欲素受体2的G1246A等位基因与丛集性头痛的药物治疗效果无关。
- In itro tests, such as radioimmunoassay, detect serum IgE antibodies to the drug responsible for the aderse reaction. 体外试验如放射免疫测定法可检测不良反应出现时药物反应的血清IgE抗体。
- This year, for the first time, scientists published studies on human diseases and drug responses using IPS cells. 今年科学家第一次发表了用IPS细胞研究人类疾病和药物反应的论文。
- The nurse diluted the drug with saline water. 护士用生理盐水把药加以稀释。
- Objectives To attempt to improve the L dopa drug response and to reduce the occurrence of complications in the patients with Parkinson disease on long term administration with L dopa drugs. 探讨对长期用左旋多巴(L-Dopa)类药物的帕金森病(PD)病人,经短期停用L-Dopa后能否提高疗效、降低L-Dopa剂量和减少并发症。 方法选择20例PD病人,均存在明显的疗效减退或药物并发症。
- Reduced antiplatelet drug responsiveness, including resistance to currently used oral antiplatelet agents, has been suggested to play a role in these worse outcomes. 降低抗血小板药物反应性已被认为在这些更糟的结果的出现中起到了推波助澜的作用,其中就包括对目前常用口服抗血小板剂的抵制。
- I hurried in response to my friend's summons for help. 我应召急忙前去帮助我的朋友。
- We are testing the efficacy of a new drug. 我们正在测试新药的功效。
- He made/gave no response to my inquiry. 他对我的询问未予回答。
- I am surprised to learn that he is taking drug. 听说他在吸毒,我很吃惊。
- His idea received an enthusiastic response. 他的想法获得热烈的响应。
- This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy. 本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
- His business was a cover for drug dealing. 他的商行是进行毒品交易的幌子。