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- OBJECTIVE To investigate the effect of Shengmai injection (SMI) on the drug metabolizing enzyme of liver in mice. 目的:观察生脉注射液(SMI)对小鼠肝药酶的影响。
- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Some applications of phenotyping &genotyping of drug metabolizing enzymes are also introduced. 最后主要讨论了表型分型和基因分型在药物代谢酶研究中的一些应用。
- Objective: To review the effects of the active components of Chinese herbs on drug metabolizing enzymes. 目的:综述近年来中药有效成分对药物代谢酶的影响的研究进展。
- With the exception of drug metabolizing enzymes, drug receptors are another important kinds of proteins involved in drug response. 这些差异的产生是遗传因素与环境因素共同作用的结果，其中遗传因素为决定性因素。
- Effect of Shengmai injection on mice's liver drug metabolizing enzyme 生脉注射液对小鼠肝药酶的影响
- Keywords nuclear receptor;drug metabolizing enzyme;xenobiotics;drug; 核受体;药物代谢酶;外源性物质;药物;
- Objective: To promote the study of drug metabolic enzymes in clinical practice. 目的:为了促进药物代谢酶在临床上的深入研究。
- Drug metabolism determines several pharmacological and toxicological properties of pharmaceuticals and is catalyzed by drug metabolizing enzymes. 药物代谢是在代谢酶催化下完成的,它决定着药物的药理学和毒理学特性。
- Effect of Combined Use of Herba Sargassii and Radix Glycyrrhizae Uralensis on Mice's Drug Metabolizing Enzyme of Liver 海藻、甘草及其相伍用对小鼠肝药酶的影响
- Keywords hepatocarcinoma;drug metabolizing enzyme;genetic polymorphism;genetic susceptibility; 肝癌;药物代谢酶;基因多态;遗传易感性;
- Drug metabolic enzymes are one of the major factors causing the variation of drug effects as well as toxicity in pa... 结论:药物代谢酶的认识和研究有助于临床合理用药和减少药物不良反应。
- For example, research in the area of polymorphism of Phase I and Phase II metabolizing enzymes, CYP mediated drug metabolisms, high throughput ADME assessment and a more molecular focus. 如，相关药物代谢酶的基因多态性及指导临床合理用药的应用、中草药与药物相互作用相关机制及在肾移植病人的应用、体外ADME高通量筛选和评价技术、中草药与药物代谢性相互作用及相关机制研究等。
- Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity. 摘要药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起著重要的作用，对组织器官的药物效应和毒性的易感性产生重要影响。
- Drug metabolism enzymes(DME) play a significant role in drug detoxification and activation,which exert important effect on drug efficacy and sensitivity to toxicity. 药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用,对组织器官的药物效应和毒性的易感性产生重要影响。
- drug metabolizing enzyme 药酶
- The genetic variations of drug related proteins including drug metabolism enzymes,drug transport proteins,and drug active receptors and/or targets are basic factors resulting in individual and ethnic differences in drug response. 除环境因素外,药物代谢酶、药物转运蛋白以及药物作用受体或靶位等药物反应相关蛋白的基因变异是引起药物反应个体差异和种族差异的根本原因。
- Exploration on effect and significance of drug metabolic enzyme for studying on compatibility of Chinese herbs 药物代谢酶在中药配伍研究中的作用
- Keywords Drug metabolism enzyme;drug transporter;single nucleotide polymorphisms; 药物代谢酶;药物转运蛋白;基因多态性;
- Keywords drug metabolism enzyme;drug-drug interaction;incompatible combination;aconitine;pregnane X receptor; 药物代谢酶;药物相互作用;配伍禁忌;乌头碱;孕烷X受体;
