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- Molecular techniques such as gene knockout partially support the monoamine theory of depression. 诸如基因部分敲除的分子技术支持抑郁症的单胺理论。
- We also detected BMD in APN gene knockout mice to evaluate the relationship between adiponectin and bone metabolism. 对骨代谢的初步研究采用检测小鼠骨密度(BMD)的方式。
- Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. (有关普罗布考对载脂蛋白E基因敲除小鼠的动脉粥样硬化的位点专一作用)。
- Conclusion: The results shows that no significant alteration on glycometabolism or bone metabolism was found in APN gene knockout mice. 结论:脂联素基因剔除小鼠在基础状态下并无显著的糖代谢和骨代谢异常。
- Methods: We detected the weight and glucose level in APN gene knockout mice and evaluated the ability of glycometabolism by GTT and ITT. 方法:采用长期追踪野生型和该基因剔除纯合子小鼠的体重和空腹血糖水平,并进行葡萄糖耐量(GTT)和胰岛素耐量(ITT)试验以评价该小鼠的葡萄糖代谢能力。
- Conclusion LPL is a key enzyme in lipid metabolism and LPL gene knockout can influence the levels of lipid in serum and tissue. 结论LPL是脂代谢的关键酶,LPL(+/-)小鼠血清及组织脂质变化显著。
- The locomotion of mtm-5 gene knockout group is obviously faster than control group, this suggests that MTM-5 also plays a negative regulation role in the muscle development. mtm-5基因敲除型线虫的运动能力明显比对照组快,暗示其可能与肌肉系统以及整体的发育存在着某种负调控的联系。
- The effects of PDGF treatment on the induction of the migration of NIH 3T3 cells,as well as p38 gene knockout on the PDGF-induced cell migration,were observed by using Transwell cell migration system. 利用Transwell细胞迁移系统来观察PDGF对NI H3T3细胞迁移的诱导作用,以及p38基因敲除对PDGF诱导的细胞迁移的影响。
- Construction of gene knockout mouse, which based on gene targeting commendably simulates the phenotype of human disease and becomes a powerful mean of cleft lip and cleft palate research. 基于基因打靶技术建立的鼠基因敲除模型很好地模拟了人类疾病的表现型,成为研究唇腭裂的一种强有力手段。
- Abstract: Regulation of specific proteins by phosphorylation is usually overlooked by standard loss-of-function approaches such as RNAi or gene knockout, which simply remove the gene or protein. 摘 要: 常规 R NA 干涉或基因敲除的功能缺失手段仅仅只是简单地移除某个基因或蛋白,而这个过程常常会掩盖磷酸化对某个特定蛋白的调节。
- Objective To identify the role of lipoprotein lipase (LPL) in lipid metabolism through the dynamic observation of lipid levels in lipoprotein lipase gene knockout heterozygous mice (LPL+/-mice). 摘要目的通过脂蛋白脂肪酶(LPL)基因敲除杂合子LPL(+/-)小鼠模型脂质代谢的动态观察,进一步明确LPL在脂代谢中的关键作用。
- Gene Knockout Mice in drug dependence research 基因敲除小鼠在药物依赖性研究中的应用
- Status Quo and Application of Gene Knockout 基因敲除技术现状及应用
- The Advances in the Research of Gene Knockout Mice 基因剔除小鼠研究的新进展
- Mdr 1a gene knockout and drug transport mdr 1a基因缺失与药物转运
- tissue plasminogen activator gene knockout mice 组织型纤溶酶原激活剂基因敲除小鼠
- 1 Alpha hydroxylase gene knockout mice 1α羟化酶基因敲除小鼠
- Study on Gene Knockout Using Red System in Shigella flexneri Red重组系统在痢疾杆菌基因敲除中的应用研究
- Study on Vitrifaction of Lats 1 Gene Knockout Mice Ovary Lats1基因敲除小鼠卵巢玻璃化冷冻的研究
- Keywords BCG;ERP gene;Gene knockout;electroporation; 卡介苗;ERP基因;基因敲除;电穿孔;