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- Using plasmid pGEM-3Zf(-) and M13mpl8 RF DNA, this thesis studied the DNA damage (DNA single strand break (SSB) and double strand break (DSB)), and gene mutation spectra induced by 30keV N+, C+ ions. 本文以质粒、噬菌体为实验材料,主要研究30keV的N~+、C~+引起的DNA分子损伤(单双链断裂)和它诱发基因突变的特点和规律。
- gene mutation spectrum 基因突变谱
- There is K14 1A domain gene mutation in this DM-EBS pedigree. 本 DM-EBS家系存在 K14的基因突变。
- Ras gene mutation in childhood AML was mainly found in M2,M4,M5 subtypes. AML患儿中ras基因突变多见于M2、M4及M5型。
- GCH 1 gene mutation is only one of reasons to the DRD patients onset. GCH-1基因突变只是部分DRD患者的发病原因。
- For instance, many primates cannot make vitamin C, because of a gene mutation. 例如,许多灵长类动物由于基因突变而不能制造维生素C。
- Gene mutations are alterations in the DNA code. 基因突变是指DNA 密码的改变。
- To investigate the relationship between isoniazid- resistance and Kat G gene mutation or deletion. 目的:探讨结核分枝杆菌异烟肼(INH)耐药与katG基因突变和缺失的关系。
- The results show that the Ve strains by ion implantation can achieve higher rate of mutation and wide mutational spectrum. 结果表明,离子注入Vc生产菌能获得较高的突变率和较广 的突变谱。
- OBJECTIVE:To analyze the relationship between Chinese DRD onset and gene mutation of guanosine triphosphate cyclohydrolase 1(GCH 1). 目的:分析国人DRD患者发病与三磷酸鸟苷环化水解酶1(GCH-1)基因突变的关系。
- APC gene mutation is a critical genetic event in both the familial and sporadic forms of colorectal tumorigenesis. 结肠腺瘤性息肉基因的突变是家族型和散发型结肠癌的发生中危险的基因事件。
- Cells with Ras gene mutation or transformed by Ras become resistant to p53 dependent apoptosis. Ras 基因转染或突变的细胞能够对DNA损伤引起的p53依赖性凋亡产生抗性。
- Study on tetrahydrobiopterin metabolism and gene mutation for dopa-responsive dystonia-a family report. 多巴反应性肌张力障碍一家系四氢生物蝶呤代谢与基因研究
- A novel SCN5A gene mutation (del D1790) associated with congenital long QT syndrome. 遗传性长QT综合征SCN5A基因delD1790新突变
- Objective To identify the COL7A1 gene mutation in a family with dy strophic epidermolysis bullosa pruriginosa. 目的鉴定一痒疹样营养不良型大疱性表皮松解症家系的基因突变,为进一步开展基因诊断和基因治疗奠定基础。
- Objective To study the gene mutation in a pedigree with Dowling-Meara type epidermolysis bullosa simplex (DM-EBS). 目的研究 Dowling-Meara亚型单纯型大疱性表皮松解症 (DM-EBS)一家系的基因突变。
- Objective: To identify gene mutation in a family with Weber-Cockayne type epidermolysis bullosa simplex (WC-EBS). 鉴定单纯型大疱性表皮松解症Weber-Cockayne亚型一家系中的基因突变位点。
- Abnormal genes mutating is the pathogeny of cancer. 癌症的病因就是反常的基因变异。
- Objective:To identify gene mutation in a family with Weber-Cockayne type epidermolysis bullosa simplex(EBS-WC). 目的:研究Weber-Cockayne亚型单纯型大疱性表皮松解症(EBS-WC)一家系的基因突变,并进行产前诊断。
- Conclusbo: It suggsts that ras gene aed p53 gene mutation may be related with L- form infedtbo. 结合提示L型感染参与了ras原癌基因激活和p53抑癌基因的失活。