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- The even linear pattern is produced because the antibody is directed against the entire glomerular basement membrane. 肿瘤细胞位于导管上皮内且没有穿透基底膜至间质。
- HS in the glomerular basement membrane (GBM) is reported to be important for charge-selective permeability. 据报道,肾小球基底膜(GBM)内的硫酸乙酰肝素(HS)对于电荷选择通透性至关重要。
- HS in the glomerular basement membrane (GBM) is reported to be important for charge-selectie permeability. 据报道,肾小球基底膜(GBM)内的硫酸乙酰肝素(HS)对于电荷选择通透性至关重要。
- Result:The AGEs and PDGF-A concentrations were all significantly increased,the glomerular basement membrane grew wider,and the mesangium expanded. 结果:糖尿病大鼠肾小球终末糖化产物增加,肾小球血小板源生长因子-A明显增高,肾小球发生基膜增厚和系膜增宽的病理变化。
- It was the podocyte that firstly formed basement membrane, and then the endothelial cells continued.Fusion of them led to the formation of a thick glomerular basement membrane. 足细胞下先出现电子密度较低的基膜,随后内皮细胞下才出现基膜,以后,二者融合形成一层电子密度较高的血管球基膜。
- RESULTS: Seven weeks after NTS injectio n, mesangial proliferation, glomerular basement membrane (GBM) thickening and bl ood capillary s cavity emphraxi s were shown in model group. 结果:注射肾毒血清(NTS)后,病理组大鼠电镜下可见明显的系膜细胞增生,系膜基质增多,毛细血管腔闭塞及上皮下、内皮下电子致密物沉积等多种病理损伤性变化。
- Result:Under electronic microscope, the OT group appeared glomerulus mesangium hyperplasia, glomerular basement membrane increased, podocyte swelled, inosculate, and the slit pore was not clearly. 结果:电镜下,OT组大鼠肾组织出现毛细血管球系膜增生,基膜基质增多,足细胞肿胀、融合,裂孔不清晰等变化;
- AIM: Glomerular hypertrophy and progressive expansion of extracelluar matrix(ECM) have been regarded as the early feature of diabetic nephropathy(DN), which leads to accumulation of mesangium matrix and thickening of glomerular basement membrane(GBM). 目的:糖尿病肾病(diabetic nephropathy,DN)早期的病理特征是肾脏肥大和细胞外基质(extracelluar matrix,ECM)的进行性积聚,导致肾小球系膜区细胞外基质成分增加和肾小球基底膜(glomerular basement membrane,GBM)弥漫性增厚。
- Then blood glucose, hemoglobin Alc (HbAlc), glomerular PKC activity, glomerular basement membrane thickness (GBMT) and urine protein/creatinine (Pr/Cr) ratio in diabetic rats were measured and compared with those in the control. 测定糖尿病大鼠血糖、糖化血红蛋白A1c(HbA1c)、PKC活性、肾小球基底膜厚度 (GB MT)和尿蛋白质 肌酐 (Pr Cr)比值 ,并与正常对照组比较。
- The thickness of glomerular basement membrane was symmetrical, the array of podocyte kept orderly, the foot process appeared light fusion occasionally and the slit pores got smaller in OS group. OS组肾小球基底膜厚度均匀,轻微增厚;
- human glomerular basement membrane 人肾小球基底膜
- Anti glomerular basement membrane antibody 抗肾小球基底膜抗体
- anti-dog glomerular basement membrane serum 抗DGBM血清, 抗犬肾小球基底膜血清
- anti-human glomerular basement membrane serum 抗人体肾小球基底膜血清
- Glomerular basement membrane(GBM) 肾小球基底膜
- dog glomerular basement membrane 犬肾小球基底膜
- renal glomerular basement membrane thickness 肾小球基底膜厚度
- collagenase solubilized glomerular basement membrane 胶原酶溶解肾小球基底膜
- Stirling JW. Glomerular basement membrane thinning is acquired in minimal 肾小球基底膜变薄与薄基底膜肾病
- Keywords irbesartan;diabetic nephropathy;glomerular basement membrane;rats; 伊贝沙坦;糖尿病肾病;肾小球基底膜;大鼠;