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- To explore the intensity of inhibitory function of Shenkang injection (SKI), a Chinese herbal recipe, and benazepril on the proliferation of human glomerular mesangial cell (MC). 目的:探讨肾康注射液与苯那普利对人肾小球系膜细胞(MC)增殖的不同抑制作用强度。
- Method:Using serumpharmacological test of Chinese medicinal herbs,we observed that how did SKI stimulates endothelin 1(ET 1) and nitric oxide(NO) secretion in cultured human glomerular mesangial cell(GMC). 方法 :采用放射免疫检测技术 ,观察SKI对体外培养人肾小球系膜细胞 (GMC)自分泌内皮素 1(ET 1)、一氧化氮 (NO)水平的影响。
- glomerular mesangial cell ( GMC ) 肾小球系膜细胞
- Objective:To investigate the mechanism inducing apptosis of human glomerular mesangial cells (Mcs) by anti Fas antibody. 目的：研究抗Fas抗体对人肾小球系膜细胞的致凋亡作用，探讨Fas?FasL在肾脏损伤中的作用。
- Objective To investigate the effect of rapamycin on cholesterol homeostasis of glomerular mesangial cells and the underlying mechanism. 摘要 目的 研究雷帕霉素对炎性反应状态下肾小球系膜细胞内脂质稳态的影响及探讨其可能机制。
- Objective:Quantitative analysis of expression of endothelin B receptor(ETB-R)gene in rat heart,liver,lung,kidney and cuItured glomerular mesangial cells(MC)were observed. 目的：定量检测B型内皮素受体（ETB－R）基因在大鼠心、肝、肺、肾等器官及培养的肾小球系膜细胞（MC）的表达。
- Objective To investigate whether aldosterone (Aldo) may be synthesized by glomerular mesangial cells and whether Aldo promotes the synthesis of fibronectin (FN) and type IV collagen in mesangial cells. 目的 证明肾脏系膜细胞能够自身合成醛固酮 ,并探讨醛固酮对系膜细胞细胞外基质生成的影响。 方法 用RT PCR法检测大鼠系膜细胞醛固酮合成酶CYP11B2mRNA表达 ,PCR产物存化后直接测序 ;
- Objective To observe the effects of high glucose on the production of tissue plasminogen activator (t PA) by human glomerular mesangial cells (MC), its binding ability to the cells, and the role of fibronectin (FN) in this event. 目的 观察高糖状态下系膜细胞与组织型纤溶酶原激活物 (Tissueplasminogen ,t PA)结合力及系膜细胞产生t PA活性改变与纤维连接蛋白 (Fibronectin ,FN)产生的影响。
- METHODS: Using serum pharmacological test of Chinese herbs, the effects of SKI on the proliferation in cultured human glomerular mesangial cells (GMC) and the level of fibronectin (FN) secretion in cultured GMC were observed. 方法 :采用血清药理学实验法 ;观察SKI对体外培养人肾小球系膜细胞 (GMC)增殖及其自分泌纤维连接蛋白(FN)水平的影响 .
- Objective To investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB(PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells. 目的研究血小板衍生生长因子BB(PDGF-BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
- Glomerular mesangial cells (GMC) 肾小球系膜细胞
- glomerular mesangial cells proliferation 肾小球系膜细胞增殖
- The Primary Culture of Glomerular Mesangial Cell from Rats and Its Identification 大鼠肾小球系膜细胞原代培养与鉴定
- Keywords lipoxin tumor necrosis factor cyclin glomerular mesangial cell signal transduction; 脂氧素;肿瘤坏死因子;细胞周期素;肾小球系膜细胞;信号转导;
- Keywords glomerular mesangial cell;morphology;cell cycle;iridosides of cornus officinalis;oxidative stress; 肾小球系膜细胞;形态学;细胞周期;环烯醚萜总苷;氧化应激;
- Keywords aloe medicated serum;glomerular mesangial cell;oxidative stress;polyol pathway; 芦荟药物血清;肾系膜细胞;氧化应激;多元醇通路;
- Keywords myriocin;glomerular mesangial cell;glucose;extracellular matrix;cellular hypertrophy; 多球壳菌素;肾小球系膜细胞;葡萄糖;细胞外基质;细胞肥大;
- Keywords The method of heat-clearing, detoxifying;the method of promoting blood flow;Lupus Nephritis （LN）;glomerular mesangial cell （GMC）;apoptosis; 清热解毒法;活血化瘀法;狼疮性肾炎;肾小球系膜细胞;细胞凋亡;
- glomerular mesangial cell 肾小球系膜细胞
- human glomerular mesangial cell 人肾小球系膜细胞
