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- Burnstein KL,Cidlowski JA.The down side of glucocorticoid receptor regulation.Mol Cell Endocrinol 1992 ,83(1):1-8. 凌昌全李敏.;中药对糖皮质激素受体保护作用的实验研究
- AIM:To further elaborate the effect of glucocorticoid receptor(GR) decrease on level of inflammatory media in rats after critical scald. 目的:阐明糖皮质激素受体(GR)减少对严重烫伤大鼠体内几种炎症介质水平的影响。
- Objective:To study on glucocorticoid receptor (GCR) activity of peripheral leukocytes in allergic rhinitis guinea-pigs with Cold or Heat Syndrome. 目的:研究寒、热证豚鼠变应性鼻炎糖皮质激素受体(GCR)活性。
- Objective To observe the changes of glucocorticoid receptor (GR) in cerebral and hepatic cytosol during decompression stress injury in rats. 目的探讨大鼠减压应激损伤时大脑和肝脏胞液糖皮质激素受体结合量的变化。
- Objective To identify the putative interaction of novel gene Ang Re m104 and glucocorticoid receptor AF-1 specific elongation factor in mammalian c ells. 目的应用免疫共沉淀技术,验证新基因AngRem104和糖皮质激素受体特异延伸因子(GR-EF)蛋白在哺乳动物细胞中的相互作用,为进一步研究AngRem104的生理功能奠定基础。
- The glucocorticoid receptor (GR) in peripheral leukocytes of adult and aged athletes was measured by radio-ligandbinding assay using [3H]dexamethasone (Dex) as the ligand. 本文以[~3H]地塞米松(Dex)为配体,用放射配体结合测定法研究了成年运动员和老年运动员外周血白细胞糖皮质激素受体(GR)的变化。
- Group C and Group D, glucocorticoid receptor antagonist RU38486 (10mg/kg bw) was given by gavage 2 hours before or after burn and endotoxin, respectively. C组于伤前 2h,D组于伤后2h分别使用糖皮质激素受体拮抗剂RU38486灌胃(10mg/kg),余处理同B组;
- Oakley RH,Sar M,Cidlowski JA.The human glucocorticoid receptor beta isoform:expression biochemical properties and putative function.J Biol Chem 1996 ,271:9550-9559. 张家庆刘志民.;阳虚患者单个核及多形核白细胞糖皮质激素受体改变[J]
- Objective In order to study the glucocorticoid receptor (GR) expression in lymphocyte and its relation with serum glucocorticosteroids contents in acute hepatitis A patients. 目的探索甲型病毒性肝炎患者外周血淋巴细胞糖皮质激素受体(GR)的表达与血清中皮质醇激素浓度的相互关系。
- Pojuls L,Mullol J,Roca-Ferrer J.Expression of glucocorticoid receptor alpha and beta isoforms in human cells and tissues.Am J Physiol Cell Physiol 2002 ,283(4):1324-1331. 凌昌全陈哲.;52例阴虚阳虚患者外周血混合白细胞糖波质激素受体的实验观察
- The expression of glucocorticoid receptor was 57.4%(35/61)in colon cancers. In the highly and moderately differentiated colon cancers the expression of GR was 64.6%(31/48), obviously higher than that in poorly differentiated colon cancers. 在61例结肠癌组织中GR表达阳性率为57.;4%25(35/61);在高、中分化的结肠癌GR阳性率64
- When injected into the brain cavity near the hippocampus, TSA increased both the amount of acetylation and the level of expression of the glucocorticoid receptor in adult rats that had had little maternal care early in life. 在早年缺少母性关怀的老鼠中,当把TSA注射入海马体附近的脑室内时,乙酰化作用被增强了,糖皮质激素受体的表达也更活跃了。
- The inhibition of F-suc was concentration-dependent and could be blocked by the antagonist of intracellular glucocorticoid receptor RU38486, but not by the protein synthesis inhibitor actidione. 糖皮质激素胞内受体阻断剂RU38486能阻断GC的快速抑制作用。 蛋白质合成抑制剂放线菌酮不能阻断该快速作用。
- A study on glucocorticoid receptor expression in PBL lymphocyte and its relation with serum glucocorticosteroid contents in type A hepatitis patients Han Huanxing, Kong Xiantao, Zhang Guozhi, et al. 单位:200003上海,第二军医大学长征医院(韩焕兴、孔宪涛、张国治、李石);第二军医大学药学系(周廷森)关键词:受体,糖皮质激素;流式细胞术;
- The effect was thought to be mediated via trabecular meshwork glucocorticoid receptors. 这种效应被认为是通过小梁网的糖皮质激素受体介导的。
- For instance,postmortem study of hippocampi from the brains of people whocommitted suicide show fewer glucocorticoid receptors comparedwith controls. 例如,与控制组比,自杀者的海马的尸检研究显示更少的肾上腺皮质激素受体。
- Objective To study the relationship between the changes of glucocorticoid receptors(GR)in peripheral leukocytes and in kidney in glomerulonephritis. 目的探讨肾炎状态下外周血白细胞糖皮质激素受体(GR)与肾胞浆GR变化的关系。
- Objective:To study the changes and significance of glucocorticoid receptors in peripheral leukocytes in patients of acute spinal cord injury. 探讨急性脊髓损伤患者外周血白细胞糖皮质激素受体的变化及其意义。
- Result:Glucocorticoid receptors binding sites in peripheral leukocytes was markedly lower in patients than in normal adults. 结果:急性脊髓损伤患者受体结合位点数明显低于正常成人组。
- Purpose: ariation in sensitiity to glucocorticoids obsered in healthy population is influenced by genetic polymorphisms of the glucocorticoid receptor gene (NR3C1). 目的:正常人群对糖皮质激素敏感性的变化受糖皮质激素受体(NR3C1)基因遗传多态性的影响。