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- AIM: To use three dimensional printing (3DP) technology to prepare zero-order controlled-release tablets of helicid. 目的:应用三维打印技术制备豆腐果苷零级控释片。
- OBJECTIVE To study the drug release mechanism of helicid(HD) bioadhesive sustained-release tablet and to determine the adhesive force in vitro. 目的研究生物黏附性神衰果素缓释片的体外释放度及释药规律,并测定其体外黏附力。
- AIM: To investigate the influence of three dimentional printing processes(3DP) on the release of controlled-release helicid tablet. 目的:研究三维打印工艺对控释片中豆腐果苷释放的影响。
- According to the physicochemical properties and absorption characteristic of Helicidum in rats, its 12h sustained-release pellets were developed in this paper. 本文选择具有镇静安眠止痛作用的豆腐果素为模型药物，根据其理化性质和胃肠道吸收特点，设计研制12h缓释微丸。
- The present invention relates to the use of the compound of helicid, or its pharmaceutically acceptable salts, esters or solvates, for the manufacture of medicaments in treating neuropathic pain. 本发明涉及豆腐果苷化合物或其可药用盐、酯或溶剂化物在制备用于治疗神经源性疼痛的药物中的用途。
- Keywords helicid;structure modification;hypnotic-sedative;1,5- benzothiazepine; 豆腐果苷;结构修饰;镇静催眠;1;5-苯并硫氮杂卓;
- Preparation of the helicid hydrophile matrix tablets and study of the drug release mechanism 神衰果素亲水凝胶缓释骨架片的制备及释药机理的研究
- Zero-order controlled-release tablets of helicid fabricated by three dimensional printing technology 三维打印技术制备豆腐果苷零级控释片研究
- Keywords three dimensional printing;helicid;zero-order controlled-release;donut-shape multi-layer tablets; 三维打印;豆腐果苷;零级控释;馅饼型多层片;
- Keywords helicid;antidepressant effect;mice tail suspension test;mice forced swimming test; 豆腐果苷;抗抑郁;悬尾;强迫游泳;
- helicidumn. 豆腐果苷
- Helicid 豆腐果甙复方阿斯匹林片; 解热止痛片; 复方乙酰水杨酸; A.;P
