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- Cytochrome P450 2D6 (CYP2D6) is an important hepatic microsomal enzyme which metabolizes clinical drugs. CYP2D6在临床重要药物代谢中具有重要作用。
- hepatic microsomal enzyme 肝微粒体酶
- Keywords genistein;pharmacokinetics;HPLC;hepatic microsome enzyme;CYP1A2;Enzyme kinetics;daidzein;P-glycoprotein;transport;accumulation; 染料木黄酮;药代动力学;高效液相色谱;肝微粒体酶;细胞色素1A2;酶动力学;大豆苷元;P糖蛋白;转运;摄取;
- hepatic microsomal enzymes 肝微粒体酶
- It seems, therefore, that 3-deoxy-HMT is a potent stimulant of the hepatic microsomal drug-metabolizing enzymes. 由此认为;3-去酮HMT可能具有刺激肝脏药物转化酶的作用.
- Objective: To observe the effects of silym arin on hepatic microsomal and mitochondrial membrane fluidity in mice. 目的 :观察水飞蓟素silymarin对小鼠肝微粒体及线粒体膜流动性的影响。
- Phenobarbital does not impair normal hepatic function but has been shown to induce liver microsomal enzymes, thus increasing and/or altering the metabolism of barbiturates and other drugs. 苯巴比妥不损害肝脏的功能,但可诱导肝微粒体酶,从而增加或改变巴比妥类和其他药物的代谢。
- Effects of EGCG on hepatic microSomal drug-metabolizing enzyme and CCl_4-induced liver injury 儿茶素对肝药酶和CCl_4急性肝损伤的影响
- Induction of microsomal enzyme activity 药酶诱导作用
- microsomal enzyme oxidizing system 微粒体酶氧化系统
- Influence of Lead Caused by the Mother Rats on the Hepatic Microsomal Drug-Metabolizing Enzyme Activities in the Descendant Rats 母源性铅接触对子代鼠肝微粒体药酶活性的影响
- After induced by AFB1 the activity of liver microsomal enzymes in duck has been studied and has been compared with the control groups respectively. 本文对1月龄麻鸭经过黄曲霉毒素诱导后在1月、1年及3年观察其肝微粒体酶(S9)的代谢活性并与各相应对照组进行比较。
- Results and Conclusion : The result s both with and without S9 (rat liver microsomal enzymes) showed that all the samples had no mutagenicity. 结果与结论:经加和不加大鼠肝脏微粒体酶(S9) 两种试验,结果全部受试物均未发现致突变毒性;
- METHODS The ultraviolet spectrophotometric method was used to measure P450 concentration of hepatic microsomes. 方法紫外分光光度法测定大鼠肝微粒体P450含量;
- Keywords microsomal enzyme;benzene;bone marrow cell;apoptosis; 微粒体酶;苯;骨髓细胞;凋亡;
- The Effects of Silymarin on Hepatic Microsomal and Mitochondrial Membrane Fluidity in Mice 水飞蓟素对小鼠肝细胞微粒体及线粒体膜流动性的影响
- The effects of DDT and DDE on membrane fluidity of the brain synaptosome, hepatic microsome and mitochondria were investigated in rat by using ANS fluorescence polarization technique. 以ANS(8-Anilinonaphthalene-1-Sulphonicacid)为荧光探剂,观察了对,对’-滴滴涕(P,P’-DDT)、对,对’-敌敌伊(P,P’-DDE)对大鼠脑突触体膜、肝线粒体膜和肝微粒体膜表层流动性及荧光参数的影响。
- The results showed that high and middle dose of Yuzhiling could apparently reduce the level of LPO and increase the activity of SOD in the hepatic microsome,which Rensheng decoction could do. 试验结果表明,大、中剂量的预知灵和人参煎液均能显著降低肝微粒体LPO水平并提高其SOD的活力。
- Study on the Reactivity of Selecting Chinese Herbal Medicine Extracts in Hepatic Microsomal and Related Free Radical Models 中药提取物在肝微粒体和相关自由基模型中反应性的筛选
- CHANGES OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE AND PLASMA SEX HORMONE LEVELS IN ADULT THYMECTOMIZED RATS AND AGED RATS 成年去胸腺大鼠和老年大鼠肝微粒体混合功能氧化酶及血浆性激素水平的变化