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- One such histone demethylase, JHDM1B, has been suggested to be a tumour suppressor. 这样一种组蛋白去甲基化酶JHDM1B曾被认为是一个肿瘤抑制因子。
- lysine-specific histone demethylase 1 组蛋白赖氨酸特异性脱甲基酶1
- histone demethylase 组蛋白去甲基化酶
- The histone code will not be easy to crack. 组织蛋白的密码不是那么容易破解的。
- A nucleoprotein whose protein component is a histone. 核组蛋白蛋白成分是组蛋白的核蛋白
- A nucleoprotein whose protein componentis a histone. 核组蛋白蛋白成分是组蛋白的核蛋白。
- Study on histone acetylation in myoblast cultures of DMD chicken embryo. 进行性肌营养不良鸡胚成肌细胞组蛋白的乙酰化研究。
- Histone acetylation/deacetylation is closely related to the regulation of gene. 组蛋白乙酰化/去乙酰化与基因调控密切相关。
- Histone lysine methylation plays a key role in epigenetic regulation. 摘要组蛋白赖氨酸的甲基化在表观遗传调控中起着关键作用。
- Histone modifications are implicated in influencing gene expression. 组蛋白修饰与影响基因表达有关。
- Many enzymes can influence the nicotine-nornicotine conversion, the methylase and demethylase are most important. 烟碱、去甲基烟碱之间的转化受多种酶调控,其中甲基化酶和去甲基酶起关键作用。
- Histone deacetylase inhibitors had been used to treat cancer and leukemia. 组蛋白去乙酰化酶抑制剂已经越来越多的被用于治疗肿瘤和白血病。
- In addition, DDB slightly increased P450 isozymes, 3A mediated erythromycin demethylase and 1A mediated 7 ethoxyresorufin O deethylase (EROD) activities. 此外 ,联苯双酯对P4 5 0 3A介导的红霉素脱甲基酶和P4 5 0 1A介导的EROD也有一定的诱导作用。
- The chromatin remodeling and histone acetylation were associated with transcription activation. 真核基因活化与染色质的重建及组蛋白的乙酰化相关。
- Su(ar)3-9 proteins attach methyl groups to the histone labeled H3 at its ninth amino acid residue, which is a lysine. 9蛋白将甲基加在组蛋白H3的第九位氨基酸残基,也就是赖氨酸残基上,从而使H3组蛋白贴上了个标签。
- The pharmacological actions of histone deacetylase inhibitors and their potential clinical uses were reviewed. 综述了组蛋白去乙酰酶抑制剂的药理作用及其临床应用前景。
- Effective inhibitor of protein kinase C (PKC)-catalyzed histone phosphorylation. 有效的PKC催化组蛋白磷酸化抑制剂。
- Z associates with functional regulatory elements, and CTCF marks boundaries of histone methylation domains. Z和功能调控元件相关,CTCF标记组蛋白甲基化区域边界。
- The level of histone acetylation plays an important role in progression, proliferation and differentiation of leukemia. 组蛋白乙酰化水平的异常在白血病的发展、增殖和分化中起着很重要的作用。
- The hypothesis of "Histone code" suggests an existing way of program information of eukaryotic gene control. 摘要“组蛋白编码”假说提示了真核生物基因调控的程序性信息的存在方式。