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- Conclusions:DOC-2 could inhibit the tumorigenesis viability of human ovarian cancer line HO-8910. 结论:DOC-2基因能明显抑制卵巢癌细胞系HO-8910的致瘤力。
- Keywords integrin-linked kinase;antisense deoxy-oligonucleotide;human ovarian cancer line;protein expression; 整合素连接激酶;反义脱氧寡核苷酸;卵巢癌细胞株;蛋白表达;
- human ovarian cancer line 卵巢癌细胞株
- Apoptosis of drug-resistant human ovarian cancer cell line COC_1/DDP induced by survivin antisense oligonucleotides. Survivin反义寡核苷酸诱导人卵巢癌耐药细胞株COC_1/DDP凋亡的实验研究
- Objective:To study the mechanism of sodium butyrate (NaB) on human ovarian cancer cell line 3AO. 目的 :研究丁酸钠逆转人卵巢癌 3AO细胞恶性表型的机制。
- Conclusion:The reconstituted SCID mouse model with human ovarian cancer cell line has been established successfully. 结论:免疫重建的荷人卵巢癌-SCID小鼠模型已初步建立成功。
- Apoptin induces apoptosis in human ovarian cancer CoC1. 凋亡素可有效诱导卵巢癌细胞CoC1凋亡。
- Survivin antisense oligonucleotides could effectively induce apoptosis of drug-resistant human ovarian cancer cell line COC1/DDP. survivin ASONs反义寡核苷酸能诱导人卵巢癌耐药细胞株COC1/DDP细胞凋亡 ,且效果显著
- Objective:To explore the molecular mechanism of topotecan-induced apoptosis in cisplatin-resistant human ovarian cancer cell line COC1/DDP. 目的探讨拓扑替康(TPT)诱导人卵巢癌顺铂耐药株COC1/DDP凋亡的内在分子机制。
- Methods: Human ovarian cancer cell line COC1 was cultured in medium containing ATRA in different concentrations in vitro. Cell proliferation inhibition was tested by MTT assay. 方法:选用人卵巢癌细胞株COC1进行体外培养,以不同浓度的ATRA处理COC1细胞,四甲基偶氮唑蓝(MTT)比色法检测细胞增殖抑制情况;
- Methods: Human ovarian cancer cell line COC1 was cultured in medium containing ATRA in different concentrations in vitro.Cell proliferation inhibition was tested by MTT assay. 方法:选用人卵巢癌细胞株COC1进行体外培养,以不同浓度的ATRA处理COC1细胞,四甲基偶氮唑蓝(MTT)比色法检测细胞增殖抑制情况;
- Abstract Objective :To observe the effect of cisplatin, taxol and adriamycin on in vitro growth as well as the nature of cell death of human ovarian cancer cell line OVCAR-3. 摘要 目的 :观察抗卵巢癌药物顺铂、紫杉醇和阿霉素对卵巢癌细胞系OVCAR-3体外生长和生存的影响并分析由它们所致的细胞死亡性质。
- Objective To investigate the inhibitory effects of rose roxburghii tratt juice(RRTJ) and morinda citrifolia juice(NoniJ) on the growth of human ovarian cancer cell line COC_2 in vitro. 目的探讨刺梨汁(RRTJ)、诺丽汁(Non iJ)及刺梨汁联合诺丽汁对卵巢癌细胞株COC2体外生长的抑制作用。
- Objective; To investigate the expressions of anti-apoptotic protein Bcl-XL,Bcl-2, cytochrome C and the caspase-3 activity in cisplatin-resistance human ovarian cancer cell line COC1/DDP and explore their correlation to the chemoresitance of COG1/DDP. 目的 探讨人卵巢癌顺铂耐药细胞株COC1/DDP中抗凋亡蛋白Bcl-XL、Bcl-2、细胞色素C的表达及半胱天冬氨酸蛋白酶-3(caspase-3)活性与人卵巢癌顺铂耐药的关系。
- ATRA can both inhibit proliferation and induce differentiation of human ovarian cancer cell line COC1.These results may provide an effective and novel approach for clinical treatment of human ovarian cancer. ATRA能明显抑制人卵巢癌细胞株COC1的生长增殖并诱导部分细胞向良性分化。
- Objective To investigate effect of apoptin gene on human ovarian cancer cell(CoC1). 目的观察凋亡素基因(VP3)在卵巢癌细胞株CoC1中诱导凋亡的情况。
- Methods Ovarian cancer cells of line COC1 originated from human ovarian serous adenocarcinoma were implanted in nude mice. Three groups were set up: two study group (MPA in different dosages) and a control group. 方法 将人卵巢癌COC1细胞制成裸鼠移植瘤模型,肿瘤形成后,将30只裸鼠随机分成对照组和2个治疗组,每组各10只。
- Methods: The expressions of Bel-XL , Bcl-2, cytochrome C and caspase-3 activity were studied by RT-CR and Western blot in the cisplatin-resistant (COC1/DDP) and cisplatin-sensitive human ovarian cancer cell line (COC1) . 方法:采用RT-PCR和Western Blot分析人卵巢癌顺铂敏感细胞株COC1和顺铂耐药株COC1/DDP中Bcl-XL、Bcl-2、细胞色素C的表达和caspase-3的活性。
- BHL-I was capable of binding to human CD3 and human ovarian cancer as detected by ELISA and by FACS analysis of T cells and SKOV3 cells, respectively. 另外,BHL-I不仅与T细胞及卵巢癌细胞(SKOV3)具有良好的结合活性,而且与其它无关肿瘤细胞的结合活性明显低于与SKOV3细胞的结合活性,说明它具有较好的靶向性及特异性。
- ObJective: To investigate the effects of tamoxifen (TAM) and medroxyprogesterone acetate (MPA) on the proliferation and apoptosis of human ovarian cancer cell. 目的:探讨三苯氧胺(tamoxifen,TAM)和甲孕酮(medroxyprogesteroneacetate,MPA)对人卵巢癌细胞增殖和凋亡的影响。