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- Objective:To explore the HLA-DR/DQ linkage disequilibrium in Chinese people and improve the accuracyof HLA typing. 目的:探讨中国人群中HLA-DR/DQ基因连锁不平衡的分布规律,提高HLA配型结果的准确性。
- Use TDTEX, we detect the presence of linkage disequilibrium between marker loci 85CA and a disease locus. 重点介绍了FCOR2和TDTEX两个功能模块的数学原理和使用方法。
- Three haplotype s linkage disequilibrium parameter have significant difference, they are A2-B52, A11-B13,A24-... A2-B52,A11-B13,A24-B52三种单倍型有显著的连锁不平衡,可能为湖南籍汉族女性特有的单倍型。
- Linkage disequilibrium (LD)-based association analysis is an effective approach to find new genes and favorable alleles. 基于连锁不平衡(LD)的关联分析是基因发掘也是等位基因发掘的有效途径。
- A number of analyses intended to understand the genome-wide patterns of polymorphism and linkage disequilibrium are being planned for inclusion in those papers. 这些文章中将有一些旨在理解全基因组范围内的多态性和连锁不平衡模式的分析。
- Researchers also are encouraged to use HapMap data to publish on the development of novel methods to analyze polymorphism, linkage disequilibrium, and association data. 同样鼓励研究者使用HapMap数据来发表分析多态性、连锁不平衡和相关数据的新方法。
- He and his colleagues reckon they can both estimate the rate of evolution and identify many of the evolving genes, by using a trick with the clumsy name of linkage disequilibrium. 他和他的同事们猜想通过应用一种叫做连接不均衡的技术,他们既能估计出进化的速度,还能鉴别出很多正在进化中的基因。
- Methods:All together 830 Chinese patients who would be given kidney transplantation were analyzed byPCR-SSP method for HLA typing to study the HLA-DR/DQ linkage disequilibrium. 方法:用PCR-SSP分型方法对HLA-DR和DQ基因座位进行基因分型,对中国人群中拟接受肾移植患者HLA型别中HLA-DR和HLA-DQ基因的连锁不平衡进行了研究。
- On the genomic mapping information linkage disequilibrium between DXS7132 and DXS6804 was showed.Female haplotypes were determined by analyzing family trios. 由于基因组作图信息显示DXS7132和DXS6804之间存在紧密连锁,故用家系分析法确定女性的单体型。
- Association analysis is an approach to identify the relationship of molecular markers or candidate genes with traits in a given population based on linkage disequilibrium (LD). 它以连锁不平衡为基础鉴定某一群体内性状与遗传标记或候选基因间的关系。
- Research and Application of Linkage Disequilibrium 连锁不平衡的研究与应用
- three-way linkage disequilibrium effect 三边连锁不平衡效应
- admixture linkage disequilibrium (ALD) 混合连锁不平衡(ALD)
- Strategties for Fine Mapping of QTL with Linkage Disequilibrium 利用连锁不平衡进行QTL精细定位的策略
- A Powerful Linkage Disequilibrium Test to Map Loci Underlying Complex Diseases 一种有效的复杂疾病基因定位的检测法
- Analysis of hepatic lipase gene polymorphism and linkage disequilibrium 肝脂酶基因启动子多态性与连锁不平衡分析
- Keywords retinitis pigmentosa;RP1;RHO;multifocal ERG;linkage disequilibrium; 视网膜色素变性;RP1基因;RHO基因;多焦视网膜电图;连锁不平衡;
- This does not explain the initial disequilibrium. 这一点并不能说明最初的不平衡。
- Gene Mapping and Genetics Model of Linkage Disequilibrium in Half-bred Human Population 人类混血群体连锁不平衡的遗传学模型与基因定位
- Linkage disequilibrium of microsatellite markers on chromosome 6 and its relationship with asthma 6号染色体微卫星标记与哮喘表型的连锁不平衡研究