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- Loteprednol etabonate was synthesized through oxidation, acylation, hydrolysis and chloromethy-lation from the starting material prednisolone. 以泼尼松龙为原料,经氧化、酰化、水解成盐、氯甲基化成酯制得氯替泼诺。
- Keywords Loteprednol Etabonate;dog;toxicity;no-toxic-effect dose; 关键词氯替泼诺;犬;长毒;无毒反应剂量;
- Keywords medicinal chemistry;preparation;chemical synthesis;loteprednol etabonate; 药物化学;制备;化学合成;氯替泼诺;
- loteprednol etabonate 氯替泼诺碳酸乙酯<局部抗炎药>
- Keywords GC;Loteprednol;methanol;ethanol; 气相色谱;氯替泼诺;甲醇;乙醇;
- Keywords intraocular pressure;endoph thalmia;meta analysis;placebos;prednisolone;loteprednol; 关键词眼内压;内眼炎;荟萃分析;安慰剂;泼尼松龙;氯替泼诺;
- etabonate 依碳酸盐[酯]
- loteprednol 氯替泼诺<肾上腺皮质激素类药; 局部抗炎药>