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- METHODS To establish a HPLC method for determing the content of ribavirin.The water-soluble matrix tablet was preparaed by use of HPMC.The optimal formulation was obtained by uniform design. 方法:建立高效液相色谱(HPLC)体外释放度测定法,以羟丙基甲基纤维素(HPMC)为主要辅料,制备亲水凝胶型骨架片,采用单因素试验筛选辅料种类,通过均匀设计优化出缓释片的处方。
- Aim The water-soluble matrix tablets were prepared b y using of HPMC (K4M) . 目的:以HPMC为主要材料,制备水溶性骨架片。
- Objective:To prepare the mixed matrix tablets of Loxoprofen sodium and to evaluate their dissolution in vitro. 目的:制备洛索洛芬钠混合性缓释片并考察其体外释放度。
- Xanthan gum hydrophilic matrix tablets were prepared using theophylline as a model drug. 以茶碱为模型药物,制备了黄原胶亲水性骨架片,研究了体外释药的影响因素。
- Objective To study the release kinetics of theophylline from the hydroxypropyl methylcellulose (HPMC) matrix tablets in vitro release test. 目的研究以羟丙基甲基纤维素(HPMC)为基材的茶碱片剂在体外溶出的动力学规律。
- Objective To investigate factors influencing the in vitro release of sulindac from the hydrogel matrix tablets and optimize the formulation. 目的 研究舒林酸亲水凝胶缓释骨架片体外释放的影响因素,筛选最优处方。
- AIM To investigate the affecting factor of the diclofenac potassium release in vitro from hydroxypopylmethylecellulose(HPMC) matrix tablets. 目的考察影响双氯芬酸钾羟丙基甲基纤维素(HPMC)骨架片体外释放的各种因素。
- OBJECTIVE:To make diclofenac sodium(DCF) hydrophilic matrix tablets and examine the factors affecting their dissolution rates. 目的:制备双氯芬酸钠(DCF)亲水凝胶骨架片,并对其释药影响因素进行了研究。
- The HPMC matrix tablets of Urpaidil were prepared by the wetmethod,using hydroxypropylmethylcellulose(HPMC)as the matrix material. 以HPMC为骨架材料,采用湿法制粒,制备了乌拉地尔缓释片。
- This kind of tablet is soluble in water. 这种药片能溶于水。
- Aspirin controlled release matrix tablets were prepared using quantitative controlling method of high speed stirring granulation technology. 用均匀设计法设计试验,对高速搅拌制粒工艺进行定量化控制,制备了阿司匹林控释骨架片。
- RESULTS:Formulation 7 had good slow releasing rate.The stabili ty test results showed that the matrix tablets were stable under the test condit ions. 结果:处方7具有很好的缓释效果,稳定性研究表明该缓释片的稳定性良好。
- Keywords Loxoprofen sodium;Mixed matrix tablet;Release velocity; 洛索洛芬钠;混合性缓释片;释药速率;
- There is a tablet in memory of those who died. 那儿有一块碑纪念死去的人。
- The extensions of dissolution of tranilast from the SR matrix tablets,to their perfect extent were 0.72%(in SGF),94.3%(in SIF) and 98.7%(in gradient pH) within 10 hours. 相同条件下 ;曲尼司特缓释片在人工胃液、人工肠液和梯度pH溶液中 ;10h的释放度分别为 0 .;72%25、94
- Results as follows: In the HPMC matrix tablets, we studied the effect of the content and the viscosity of HPMC, particle size of MNZ, shape and weight of ta. 结果如下:以HPMC为辅料的骨架片,考察了HPMC含量、HPMC粘度、甲硝唑粒度、片剂形状、片重、释放介质对药物释放的影响。
- Take two of the tablet three times daily before meals. 每日三次,每次两片,饭前服用。
- Fill a glass with water and dissolve this tablet in it. 倒杯水把药片放进去溶解了。
- A term sometimes applied to a stylus in a thermal matrix printer. 有时用来指热敏点阵打印机的触针的一个术语。
- Result The sorts, model and amounts of matrix materials had remarkable influence on the release mechanism of sulindac from the matrix tablets, while the influence of the selected fillers was marginal. 结果 骨架材料的种类、型号及用量对舒林酸释放机制影响较大,填充剂对舒林酸释放有一定影响。