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- Keywords hepatitis B;vaccine;adjuvant;muramyl dipeptide;muramyl dipeptide analogue;cellular immune; 乙型肝炎;疫苗;佐剂;胞壁酰二肽;胞壁酰二肽类似物;细胞免疫;
- threonine muramyl dipeptide 苏氨酸胞壁酰二肽
- muramyl dipeptide 胞壁酰二肽
- muramyl dipeptide(MDP) 胞壁酰二肽[常用作佐剂]
- Synthetic organic compound (a dipeptide) of phenylalanine and aspartic acid. 由苯丙氨酸（phenylalanine）和天门冬氨酸合成的有机化合物（二）。
- The fast atom bombardment mass spectra (FABMS) of five underivatized and seven derivatized muramyl peptides (MPs)were recorded. 本文报道12个合成的胞壁酰肽及其类似物的FABMS。
- Aspartame: Synthetic organic compound (a dipeptide) of phenylalanine and aspartic acid. 天门冬氨醯苯丙氨酸甲酯:由苯丙氨酸和天门冬氨酸合成的有机化合物。
- Results This dipeptide was confirmed good in quality by physico-chem ical determination. 结果合成的双肽经理化检测，质量高。
- Objective To explore the method of chemical synth esis of L-alanyl-L-glutamine dipeptide. 目的探讨L-丙氨酰-L-谷氨酰胺双肽的化学合成方法。
- Conclusion Dipeptide synthetized by this me thod is simple, convenient and with good guality. 结论采用本法合成谷氨酰胺双肽具有简便、快速、质量高等优点。
- The rest of desired dipeptide aldehydes were prepared by oxidation of their dipeptide alcohols. 然后在Parikh-Doering条件下氧化二肽醇，所得产物通过LC/MS制备分离得到二肽醛。
- The conformations of serine and threonine dipeptide in gas are explored using ABEEM/MM fluctuating model. 相对其他极化力场模型,该模型具有计算量较小的特点。
- Methods: Diester,diimide and dipeptide mimic compounds were synthesized by conjugated the amino groups and acid groups with diols or diacids links. 方法:通过酯化、酰胺反应由不同的二醇或二酸连接加巴喷丁和普瑞巴林合成二酯、酰胺、拟肽类等化合物。
- Methods L-alanyl-L -glutamine dipeptide was prepared by condensation and ammoniation reaction of L -glutamine and 2-D-chloropropionyl chloride. 方法以L-谷氨酰胺和2-D-氯丙酰氯为原料，通过缩合、胺化等反应，合成L-丙氨酰-L-谷氨酰胺双肽；
- The Boc protected phenylalanine (Boc-Phe-OH) reacted with phenylalanine amide to give the first dipeptide Boc-Phe-Phe-NH_2 in 86% yield. 以叔丁氧羰酰基(Boc)作为苯丙氨酸的氨基保护基，先制备苯丙氨酸酰胺三氟乙酸盐，再用叔丁氧羰酰基(Boc)保护的苯丙氨酸与其缩合得二肽片段Boc-Phe-Phe-NH_2，产率86%25。
- Gly-Asp(OBzl) 2 dipeptide was synthesized by DCC method,then Boc-Arg(NO 2 )-Gly-Asp(OBzl) 2 was synthesized by the method of mixed anhydrides. 采用二环己基碳二亚胺法(DCC)合成了二肽Gly Asp(OBzl) 2 ,然后利用混合酸酐法得到全保护RGD三肽:Boc Arg(NO2 ) Gly Asp(OBzl) 2 三肽;
- Carnosine is a kind of dipeptide in muscle.We pay much more attention on carnosine because of its high effect and low toxicity. 摘要肌肽是主要存在动物肌肉中的二肽，作为一种新型高效低毒的天然抗氧化剂日益受到关注。
- In this study, a novel chemical method was used to prepare the precursor dipeptide Gly-Asp diamide of RGD at large scale with low cost. 因此本文根据 RGD 的化学结构特点,采用化学- 酶法相结合的RGD 合成策略:先用新颖的化学法得到产量较高的前体GD 二肽酰胺,这一步反应操作简单，而且成本低廉；
- Moreover,the stabilization of the complexes,especially the influence of the optical activity of dipeptide on the stabilization has been discussed. 对配合物的稳定性进行了讨论,着重介绍了二肽的光学异构对配合物稳定性的影响。
- The interaction of leucine dipeptide with calf thymus DNA was studied by UV-visible spectroscopy,circulating voltammetry and viscosity measurement. 利用紫外-可见光谱法、循环伏安法和黏度法研究了亮氨酸二肽与小牛胸腺DNA的相互作用。
