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- mutational heteroduplex 突变的异复式, 突变的异源双链
- Objective To compare the effectiveness of heteroduplex, SSCP and heteroduplex-SSCP analyses in mutational screening. 目的比较异源双链、单链构像多态(SSCP)、异源双链-SSCP法筛查突变的效率,寻找简便有效的基因突变筛查方法。
- Conclusion Heteroduplex-SSCP analysis is simple, economical and more effective than SSCP or heteroduplex analysis alone and it may be widely applied in mutational screening. 结论异源双链-SSCP法突变检出率高,经济、简便,值得在基因突变筛查中推广应用。
- All sorts of mutational damage to animals' DNA would have occurred. 动物的脱氧核糖核酸可能遭到了各种各样的突变破坏。
- All sorts of mutational damage to animals'DNA would have occurred. 动物的脱氧核糖核酸可能遭到了各种各样的突变破坏。
- TP53 mutational status was compared with clinical outcome. 同时比较了TP53突变状况与临床结果的关系。
- Nelson H, Nelson N. title Cloning and mutational analysis of t ... 而在NCBI上的人体驱动蛋白马达域的 ...
- Objective To study the sensitivity and specificity of gene mutational analysis. 目的本文对脊肌萎缩症基因诊断的敏感性与特异性进行了研究。
- Methods We used heteroduplex mobility analysis (HMA) and sequencing to detect mixed infection. 方法使用异双体动态分析法和测序检测混合感染。
- These large populations facilitate the detection of rare mutational or recombinational events. 这样的大群体有利于检出稀有的突变或重组子。
- The PCR products were then analyzed by heteroduplex, SSCP and heteroduplex-SSCP analyses separately to testify the effectiveness of each method. 方法应用聚合酶链反应(PCR)扩增23个已知的杂合子突变,分别以异源双链、SSCP、异源双链-SSCP法分析突变,对比各方法对突变的检出情况。
- Results Of the 23 mutations, 22 were detected by heteroduplex analysis (96%), 20 by SSCP analysis (87%) and 23 by heteroduplex-SSCP analysis (100%). 结果23个杂合子突变中,异源双链法、SSCP法与异源双链-SSCP法检出突变分别为22个(96%25)、20个(87%25)和23个(100%25)。
- Methods The microsatellite polymorphism of MICA exon 5 in 175 unrelated healthy individuals were investigated using PCR heteroduplex analysis. 方法用PCR-异源双链分析法,对175名正常无关个体的MICA基因第5外显子微卫星多态性的分布进行研究。
- Set an objectively scientific foundation for name, diagnosis, therapy and assessment of mutational falsetto. 目的 :为变声后“假声”的命名、诊断、治疗及疗效评价提供科学、客观的理论依据。
- Doramectin, which is manufactured by mutational biosynthesis method, is a novel avermectin derivative. 道拉菌素是利用生物突变合成方法得到的新型阿维菌素族广谱抗寄生虫药。
- Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma. BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。
- Conclusion The PCR-SSP may be used for genotyping in mutational mononucleatide,and it has a good prospects. 结论PCR-SSP可对具有单核苷酸突变的基因分型,应用前景良好。
- Conclusion The PCR-SSP may be used for genotyping in mutational mononucleatide, and it has a good prospects. 结论PCR-SSP可对具有单核苷酸突变的基因分型,应用前景良好。
- Some drugs are showing like a five-year mutational rate as high as 70%, but other drugs showing maybe less than 5%. 一些药物5年出现变异耐药的几率为70%25,而别的药物可能少于5%25。
- Objective: To observe the mutational pattern of STR loci in parentage testing cases. 摘要目的:观察亲子鉴定中STR基因座的突变方式。