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- The finding of Neurotrophic Factors( NTF) bring about new hope for SCI. 神经营养因子(Neurotrophic Factors,NTF)的发现为脊髓损伤的治疗带来了新的希望。
- The smrvival of neurons in vitro is an important indcx to evalutate thc trophic effect of neurotrophic factors (NTFs). 神经元在体外的存活是衡量一种营养因子有无神经营养作用的重要指标之一。
- The mechanism of stem-cell therapy includes cell-replacement, delivery neurotrophic factors and immunomodulation. 其治疗的作用机制主要分为3种:细胞替代、神经营养因子释放和免疫调节。
- The article reviews the discovery,effect and mechanism of these neurotrophic factors that secreted by BMSCs no matt... 现就骨髓基质细胞在体内或体外分泌的多种神经营养因子的发现、作用及机制进行综述。
- A lot of neurotrophic factors (NTFs) including NGF, BDNF, FGF, and CNTF can promote RGCs survival both in vitrol and in vivo. 研究证实多种NTFs(如NGF、BDNF、FGF、CNTF)对体外培养及视神经横断伤后RGC的存活有明显促进作用,为轴突再生提供了前提条件。
- Objective: To investigate the effect of neurotrophic factors derived from Schwann cell (Sc?NTFs) on injured spinal cord. 目的:观察雪旺细胞源神经营养因子(Sc-NTFs)对损伤脊髓组织的作用。
- In the process of development and regeneration of nervous system, it act as neurotrophic factor. 在神经系统发育和再生过程中,肝细胞生长因子作为神经营养因子发挥作用。
- Insulin like growth factors also have a modulatory role in neuronal function.Insulin and neurotrophic factors including insulin ... 同样,胰岛素样生长因子对神经元功能也有一定的调节作用。
- These data suggest that combining neurotrophic factors of differing modes of action likely enhance the outcome from "chronic" SCI. 这些数据表明,联合应用不同作用方式的神经营养因子可能提高慢性脊髓损伤的预后。
- To date, the most potent of these chemicals is glial-cell-line deried neurotrophic factor (GDNF). 迄今为止,在这些化学物质之中效果最好的就是神经胶质细胞源性的神经营养因子。
- Objective To investigate the role of ciliary neurotrophic factor (CNTF) in injury of central neuron. 目的研究睫状神经生长因子(CNTF)在中枢神经元抗损伤中的作用及机制。
- Whether or not neurons hae a long and healthy life is, apart from other factors, determined by the presence of neurotrophic factors. 除其它因素之外,通过神经营养的因子存在与否决定神经元是否具有长久及健康的生命。
- Objective To investigate the effects of glial cell line derived neurotrophic factor in human inflammatory pulp. 目的探讨胶质源性神经营养因子(GDNF)在人炎症牙髓中的表达及意义。
- Objective To explore the changes of brain-derived neurotrophic factor(BDNF) after repeated febrile seizures (FS). 目的探讨大鼠反复高热惊厥(FS)后脑源性神经营养因子(BDNF)的变化。
- In the process of development and regeneration of nervous system,it act as neurotrophic factor. 在神经系统发育和再生过程中,肝细胞生长因子作为神经营养因子发挥作用。
- Based on that , application of neurotrophic factors and cellular transplant therapy might be developed to treat spinal cord injury in the future. 应用神经营养因子、细胞移植治疗脊髓损伤的研究正在迅速发展中。
- This paper reviewed the effect of some major neurotrophic factors on diabetic neuropathy and their application in clinical treatment. 本文对一些主要的神经营养因子对糖尿病性神经病理变性及再生作用,以及神经营养因子在临床糖尿病性神经变性的应用研究作-综述。
- Neurotrophic factors (NTFs) are a group of cytokines, which all play important roles in the differentiation, development, growth and regeneration of nerve system. 神经营养因子(Neurotrophic factors,NTFs)是一类由神经元、神经支配的靶组织或胶质细胞产生的能促进中枢和外周神经分化、生长和存活的活性蛋白质。 该蛋白在神经系统的发育和正常生理功能的维持等方面起着重要作用。
- Using the neurotrophic factors(NTFs)administrated to the PD rats, BDNF, bFGF can enhance and protect the dotaminergic neurons against 6 OHDA neurotoxin. 采用本实验给药方式 ,BDNF和bFGF能保护中脑多巴胺能神经元免于 6 OHDA的损害 ,NGF、PDGF、IL 6对其无保护作用。
- Synaptic actions of brain-derived neurotrophic factor (BDNF) are "gated"by cAMP, but the underlying molecular mechanisms remain unclear. 脑源性神经营养因子(BDNF)的突触活动受到环腺苷酸(cAMP)的门控调节,但是这种调节机制还不清楚。